ABSTRACT L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in
mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple …

Filamentous fungi can produce many valuable secondary metabolites; among these fungi,
endophytic fungi play an ecological role in mutualistic symbiosis with plants, including …

Amino acid metabolism is crucial for fungal growth and development. Ureohydrolases
produce amines when acting on l-arginine, agmatine, and guanidinobutyrate (GB), and …

Abstract Background For Aspergillus niger, a broad set of auxotrophic and dominant
resistance markers is available. However, only few offer targeted modification of a gene of …

Enzymes of the ureohydrolase superfamily are specific in recognizing their substrates. While
looking to broaden the substrate specificity of 4-guanidinobutyrase (GBase), we isolated a …

Agmatine, a significant polyamine in bacteria and plants, mostly arises from the
decarboxylation of arginine. The functional importance of agmatine in fungi is poorly …

To improve the gene targeting frequency (GTF) in the lignocellulolytic filamentous fungus
Penicillium oxalicum HP7-1, the non-homologous end-joining (NHEJ) gene ligD was …

Aspects of manganese metabolism during normal and acidogenic growth of Aspergillus
niger were explored. Arginase from this fungus was a Mn [II]-enzyme. The contribution of the …

The genus Aspergillus covers a diverse group of filamentous fungi including industrially
important species like A. niger, A. oryzae, A. awamori, A. sojae and A. terreus. Species of …

Selectable markers constitute essential genetic tools in fungal transformation. Markers find
increased application with the availability of complete genome sequences of many …