Inotropes have been fundamental to resuscitation of acute cardiogenic shock for decades.
Heart failure and cardiogenic shock, in severe cases, are syndromes characterized in many …

The HeartMate 3 left ventricular assist system (LVAS; St. Jude Medical, Inc., formerly
Thoratec Corporation, Pleasanton, CA) was recently introduced into clinical trials for durable …

Background Continuous-flow left ventricular assist systems increase the rate of survival
among patients with advanced heart failure but are associated with the development of …

We propose that stage D advanced heart failure be defined as the presence of progressive
and/or persistent severe signs and symptoms of heart failure despite optimized medical …

Importance Left ventricular assist devices (LVADs) are well established in the treatment of
advanced heart failure, but it is unclear whether outcomes are different based on the …

Durable left ventricular assist devices (LVADs) have not only enhanced longevity but also
conferred sustained improvements in quality of life, symptom control, and functional capacity …

The biggest limitation of the old, 3-tiered system included inadequate risk estimation as
patients listed as status 1A (high priority) comprised a heterogeneous group with differing …

Importance The mortality rate for the most advanced forms of heart failure with medical
therapy alone remains unacceptably high at 30% to 80% at 1 year. In the past decade, left …

2672 Circulation June 21, 2016 indication narrowed to include only those with left
bundlebranch block configuration as the driver of the wide QRS, 13 based both on clinical …

Mechanical circulatory support has seen numerous advances in the recent years, with
important observations made to guide patient selection for the therapy, indications for use …