NANOBODY®(a registered trademark of Ablynx NV) molecules (Nbs), also referred to as
single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG …

Unique, functional, homodimeric heavy chain–only antibodies, devoid of light chains, are
circulating in the blood of Camelidae. These antibodies recognize their cognate antigen via …

A nanobody (Nb) is a registered trademark of Ablynx, referring to the single antigen‐binding
domain of heavy chain‐only antibodies (HCAbs) that are circulating in Camelidae. Nbs are …

Antibodies have proven to be central in the development of diagnostic methods over
decades, moving from polyclonal antibodies to the milestone development of monoclonal …

Camelidae derived single-domain antibodies (sdAbs), commonly known as nanobodies
(Nbs), are the smallest antibody fragments with full antigen-binding capacity. Owing to their …

Animal African trypanosomosis (AAT), a disease affecting livestock, is caused by parasites of
the Trypanosoma genus (mainly T. vivax and T. congolense). AAT is widespread in Sub …

Nanobodies (Nbs) are increasingly recognized as valuable biological molecules with
significant potential in the field of diagnostics. Their unique physiochemical characteristics …

Background: The discovery of functional heavy chain-only antibodies devoid of light chains
in sera of camelids and sharks in the early nineties provided access to the generation of …

Trypanosoma congolense and T. vivax are the main causative agents of animal African
trypanosomosis (AAT), a disease which hinders livestock production throughout sub …

The scarcity of reliable devices for diagnosis of Animal African trypanosomiasis (AAT)
presents a limitation to control of the disease. Existing high-sensitivity technologies such as …