The non-selective cytotoxicity of toxins limits the clinical relevance of the toxins. In recent
years, toxins have been widely used as warheads for antibody‒drug conjugates (ADCs) …

Most patients with pleural mesothelioma (PM) present with symptomatic pleural effusion. In
some patients, PM is only detectable on the pleural surfaces, providing a strong rationale for …

The design of nanomaterial-based nucleic acid formulations is one of the biggest
endeavours in the search for clinically applicable gene delivery systems. Biopolymers …

Cellular senescence is considered an important tumour suppression mechanism in
response to damage and oncogenic stress in early lesions. However, when senescent cells …

Size-controlled drug delivery systems (DDSs) have gained significant attention in the field of
pharmaceutical sciences due to their potential to enhance drug efficacy, minimize side …

Since the advent of nanomedicine, physicians have harnessed these approaches for the
prophylaxis, detection, and therapy of life-threatening diseases, particularly cancer …

Metal ion-driven, DNA-cleaving DNAzymes are characterised by high selectivity and
specificity. However, their use for metal ion sensing remains largely unexplored due to long …

Background Tyrosine kinase inhibitors (TKI) have been highlighted for the therapy of non-
small-cell lung cancer (NSCLC), due to their capability of efficiently blocking signal pathway …