The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation

VT Ho, RJ Soiffer - Blood, The Journal of the American Society …, 2001 - ashpublications.org
Despite significant progress in the past 20 years, graft-versus-host disease (GVHD) remains
a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell …

Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy

S Siena, R Schiavo, P Pedrazzoli… - Journal of Clinical …, 2000 - ascopubs.org
PURPOSE: To review recent advances in peripheral-blood progenitor-cell (PBPC)
transplantation in order to define the optimal cell dose required for autologous and …

Terrestrial plant-derived anticancer agents and plant species used in anticancer research

SE Kintzios - Critical reviews in plant sciences, 2006 - Taylor & Francis
Cancer is a major cause of death and the number of new cases, as well as the number of
individuals living with cancer, is expanding continuously. Due to the enormous propensity of …

CD52 antibodies for prevention of graft-versus-host disease and graft rejection following transplantation of allogeneic peripheral blood stem cells

G Hale, P Jacobs, L Wood, WE Fibbe… - Bone marrow …, 2000 - nature.com
Graft-versus-host disease (GVHD) is a major cause of mortality and morbidity after
allogeneic bone marrow transplantation, but can be avoided by removing T lymphocytes …

The number of donor CD3+ cells is the most important factor for graft failure after allogeneic transplantation of CD34+ selected cells from peripheral blood from HLA …

A Urbano-Ispizua, C Rozman… - Blood, The Journal …, 2001 - ashpublications.org
This study analyzed the characteristics of 257 HLA-identical sibling transplants of
granulocyte colony-stimulating factor–mobilized peripheral blood progenitor cells depleted …

Comparison of the classic Glucksberg criteria and the IBMTR Severity Index for grading acute graft-versus-host disease following HLA-identical sibling stem cell …

R Martino, P Romero, M Subirá, M Bellido… - Bone marrow …, 1999 - nature.com
Acute graft-versus-host disease (AGVHD) severity is usually graded (grades 0–IV) by the
pattern of organ involvement using the classic Glucksberg–Seattle criteria (GSC). Recently …

Allogeneic transplantation: peripheral blood vs. bone marrow

WI Bensinger - Current opinion in oncology, 2012 - journals.lww.com
Allogeneic transplantation: peripheral blood vs. bone marrow : Current Opinion in Oncology
Allogeneic transplantation: peripheral blood vs. bone marrow : Current Opinion in Oncology …

Transplantation of highly purified CD34+ progenitor cells from unrelated donors in pediatric leukemia

P Lang, R Handgretinger, D Niethammer… - Blood, The Journal …, 2003 - ashpublications.org
Unrelated donors are commonly used for hematopoietic stem cell transplants, but graft-
versus-host disease (GVHD) is a major problem. We investigated whether transplantation of …

Allogeneic transplantation of CD34+ selected cells from peripheral blood from human leukocyte antigen–identical siblings: detrimental effect of a high number of …

A Urbano-Ispizua, E Carreras, P Marı́n… - Blood, The Journal …, 2001 - ashpublications.org
Clinical results after T-cell–depleted allografts might be improved by modifying the graft
content of progenitor and accessory cells. Although the association of the number of donor T …

Risk factors for acute graft-versus-host disease in patients undergoing transplantation with CD34+ selected blood cells from HLA-identical siblings

A Urbano-Ispizua, C Rozman… - Blood, The Journal …, 2002 - ashpublications.org
A study on 315 patients undergoing transplantation with CD34+ selected blood cells from
HLA-identical siblings was performed to determine risk factors for acute GVHD (aGVHD) …