Treatment technologies to mitigate the harmful effects of recalcitrant fluoroquinolone antibiotics on the environ-ment and human health

P Mathur, D Sanyal, DL Callahan, XA Conlan… - Environmental …, 2021 - Elsevier
Antibiotic proliferation in the environment and their persistent nature is an issue of global
concern as they induce antibiotic resistance threatening both human health and the …

Evaluating metabolic stress and plasmid stability in plasmid DNA production by Escherichia coli

F Silva, JA Queiroz, FC Domingues - Biotechnology advances, 2012 - Elsevier
In the context of recombinant DNA technology, the development of feasible and high-
yielding plasmid DNA production processes has regained attention as more evidence for its …

Emerging contaminants and nutrients synergistically affect the spread of class 1 integron-integrase (intI1) and sul1 genes within stable streambed bacterial …

J Subirats, X Timoner, A Sànchez-Melsió, JL Balcázar… - Water research, 2018 - Elsevier
Emerging contaminants and nutrients synergistically affect the spread of class 1 integron-integrase
(intI1) and sul1 genes within stable streambed bacterial communities - ScienceDirect Skip to …

Occurrence, source apportionment and source-specific risk assessment of antibiotics in a typical tributary of the Yellow River basin

L Wang, Y Wang, H Li, Y Zhu, R Liu - Journal of Environmental …, 2022 - Elsevier
The spatial distributions, sources, and source-specific risk apportionments of 26 antibiotics
(5 categories) in the Fenhe River basin were determined based on sample data. The results …

Degradation of fluoroquinolone antibiotics and identification of metabolites/transformation products by liquid chromatography–tandem mass spectrometry

AS Maia, AR Ribeiro, CL Amorim, JC Barreiro… - … of Chromatography A, 2014 - Elsevier
Antibiotics are a therapeutic class widely found in environmental matrices and extensively
studied due to its persistence and implications for multi-resistant bacteria development. This …

Escherichia coli adhesion, biofilm development and antibiotic susceptibility on biomedical materials

LC Gomes, LN Silva, M Simões, LF Melo… - … Research Part A, 2015 - Wiley Online Library
The aim of this work was to test materials typically used in the construction of medical
devices regarding their influence in the initial adhesion, biofilm development and antibiotic …

Investigating the antibacterial activity of salen/salophene metal complexes: Induction of ferroptosis as part of the mode of action

D Baecker, Ö Sesli, L Knabl, S Huber… - European Journal of …, 2021 - Elsevier
The continuous increase of resistant bacteria including Staphylococcus aureus and its
methicillin-resistant phenotype (MRSA) is currently one of the major challenges in medicine …

Cetylpyridinium chloride chitosan blended mucoadhesive buccal films for treatment of pediatric oral diseases

D Abouhussein, MA El Nabarawi, SH Shalaby… - Journal of Drug Delivery …, 2020 - Elsevier
Oral diseases as gingivitis, periodontitis, aphthous ulcers and dental caries are widespread
in infants and children especially in developing countries. In this study, different …

Polyvinylpyrrolidone/hyaluronic acid-based bilayer constructs for sequential delivery of cutaneous antiseptic and antibiotic

M Contardi, D Russo, G Suarato… - Chemical Engineering …, 2019 - Elsevier
After a skin injury, many complex metabolic events are triggered to ensure proper wound
healing. Particularly for chronic, non-healing wounds or burns several risk factors such as …

Cationic, amphipathic small molecules based on a triazine-piperazine-triazine scaffold as a new class of antimicrobial agents

SD Kumar, JH Park, HS Kim, CD Seo, C Ajish… - European Journal of …, 2022 - Elsevier
Poor proteolytic resistance, toxicity and salt/serum sensitivity of antimicrobial peptides
(AMPs) limits their practical clinical application. Here, to overcome these drawbacks of AMPs …