We review here the recently emerging relationship between epithelial-mesenchymal
transition (EMT) and breast cancer stem cells (BCSC), and provide analyses of published …

Resistance to chemotherapy is a major obstacle to the effective treatment of many tumor
types. Although many anticancer therapies can alter tumor growth, in most cases the effect is …

Cells with distinct phenotypes including stem-cell-like properties have been proposed to
exist in normal human mammary epithelium and breast carcinomas, but their detailed …

Breast cancers have been increasingly recognized as malignancies displaying frequent
inter-and intra-tumor heterogeneity. This heterogeneity is represented by diverse subtypes …

The identification of mammary epithelial stem cells raises the hypothesis that these cells
may be crucial in the pathogenesis of breast cancer. To further support this, a highly …

Background Cancer stem cells exhibit close resemblance to normal stem cells in phenotype
as well as function. Hence, studying normal stem cell behavior is important in understanding …

Objective (s): Berberine, a naturally occurring isoquinoline alkaloid, has shown antitumor
properties in some in vitro systems. But the effect of berberine on breast cancer has not yet …

Epithelial–mesenchymal transition (EMT) generates tumor cells with stem cell properties.
The aim of our study was to investigate the effects of adipose tissue‐derived stem cells …

The major components of the mammary ductal tree are an inner layer of luminal cells, an
outer layer of myoepithelial cells, and a basement membrane that separates the ducts from …

This study was undertaken to observe the effects and possible mechanism of CC chemokine
ligand 5 (CCL5) on invasion, proliferation and percentage of CD44+/CD24− subpopulation …