Targeting Nrf2/Keap1 signaling pathway by bioactive natural agents: Possible therapeutic strategy to combat liver disease

R Jayasuriya, U Dhamodharan, D Ali, K Ganesan, B Xu… - Phytomedicine, 2021 - Elsevier
Background Nuclear factor erythroid 2-related factor (Nrf2), a stress-activated transcription
factor, has been documented to induce a defense mechanism against oxidative stress …

Oxidative stress and liver cancer: etiology and therapeutic targets

Z Wang, Z Li, Y Ye, L Xie, W Li - Oxidative medicine and …, 2016 - Wiley Online Library
Accumulating evidence has indicated that oxidative stress (OS) is associated with the
development of hepatocellular carcinoma (HCC). However, the mechanisms remain largely …

Anti-oxidative effects of curcumin on immobilization-induced oxidative stress in rat brain, liver and kidney

S Samarghandian, M Azimi-Nezhad… - Biomedicine & …, 2017 - Elsevier
Restraint stress has been indicated to induce oxidative damage in tissues. Several
investigations have reported that curcumin (CUR) may have a protective effect against …

Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste …

M Javed, MI Ahmad, N Usmani, M Ahmad - Scientific reports, 2017 - nature.com
Experiments were conducted to investigate the health of fish Channa punctatus inhabiting
heavy metal-loaded waste water. Heavy metals in the order of Fe> Mn> Zn> Co> Ni> Cu= Cr …

Protective effects of carvacrol against oxidative stress induced by chronic stress in rat's brain, liver, and kidney

S Samarghandian, T Farkhondeh… - Biochemistry …, 2016 - Wiley Online Library
Restraint stress may be associated with elevated free radicals, and thus, chronic exposure to
oxidative stress may cause tissue damage. Several studies have reported that carvacrol …

Free radicals, antioxidants, nuclear factor‐E2‐related factor‐2 and liver damage

E Ramos‐Tovar, P Muriel - Journal of Applied Toxicology, 2020 - Wiley Online Library
Oxidative/nitrosative stress is proposed to be a critical factor in various diseases, including
liver pathologies. Antioxidants derived from medicinal plants have been studied extensively …

[HTML][HTML] Protective effects of Crocus sativus L. extract and crocin against chronic-stress induced oxidative damage of brain, liver and kidneys in rats

AR Bandegi, A Rashidy-Pour, AA Vafaei… - Advanced …, 2014 - ncbi.nlm.nih.gov
Purpose: Chronic stress has been reported to induce oxidative damage of the brain. A few
studies have shown that Crocus Sativus L., commonly known as saffron and its active …

Heme oxygenase-1 (HO-1) regulates Golgi stress and attenuates endotoxin-induced acute lung injury through hypoxia inducible factor-1α (HIF-1α)/HO-1 signaling …

X Li, J Yu, L Gong, Y Zhang, S Dong, J Shi, C Li… - Free Radical Biology …, 2021 - Elsevier
Sepsis caused acute lung injury (ALI) is a kind of serious disease in critically ill patients with
very high morbidity and mortality. Recently, it has been demonstrated that Golgi is involved …

Effects of dietary glutamine supplementation on heat-induced oxidative stress in broiler chickens: a systematic review and meta-analysis

CM Ncho, V Gupta, YH Choi - Antioxidants, 2023 - mdpi.com
In avian species, heat stress (HS) is usually the result of being exposed to high ambient
temperatures, whereas oxidative stress (OS) results from the overproduction of reactive …

Evaluation of lasting effects of heat stress on sperm profile and oxidative status of ram semen and epididymal sperm

TRS Hamilton, CM Mendes, LS Castro… - Oxidative Medicine …, 2016 - Wiley Online Library
Higher temperatures lead to an increase of testicular metabolism that results in spermatic
damage. Oxidative stress is the main factor responsible for testicular damage caused by …