As cognitive impairments continue to rise in prevalence, there is an urgent need to
understand the mechanisms of learning and memory in normal and disordered states. C–C …

The transforming growth factor-β (TGF-β) signaling pathway serves critical functions in CNS
development, but, apart from its proposed neuroprotective actions, its physiological role in …

Abstract C–C chemokine receptor 5 (CCR5) is a chemokine receptor involved in immune
responses and a co-receptor for HIV infection. Recently, CCR5 has also been reported to …

As a main clinical feature of obstructive sleep apnea (OSA), intermittent hypoxia (IH) induces
oxidative stress, leading to damage to a variety of organs, including kidney. Metallothionein …

A major challenge in neuroscience is to pinpoint neurobiological correlates of specific
cognitive and neuropsychiatric traits. At the mesoscopic level, promising candidates for …

Exposure to electric foot-shocks can induce in rodents contextual fear conditioning,
generalization of fear to other contexts and sensitization of the hypothalamic-pituitary …

Learning is a critical behavioral process that is influenced by many neurobiological systems.
We and others have reported that acetylcholinergic signaling plays a vital role in learning …

We report here a comparative analysis of the acquisition of a conditioned passive avoidance
reaction in mice of the mutant strains DISC1-Q31L and DISC1-L100P and mice of the control …

Abstract Background Murine models of Alzheimer's disease (AD) are mainly based on
overexpression of pathologic amyloid precursor protein and/or presenilins. Those genes …

Проведен сравнительный анализ выработки условной реакции пассивного избегания у
мышей мутантных линий DISC1-Q31L и DISC1-L100P относительно мышей …