The relationship between metabolism and cell cycle progression is complex and
bidirectional. Cells must rewire metabolism to meet changing biosynthetic demands across …

With the rapid development of systems and synthetic biology, the non-model bacteria,
Halomonas spp., have been developed recently to become a cost-competitive platform for …

The turnover number k cat, a measure of enzyme efficiency, is central to understanding
cellular physiology and resource allocation. As experimental k cat estimates are unavailable …

Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration
of the relation between genotype and phenotype. Streamlined integration of enzyme …

Genetically identical cells are known to differ in many physiological parameters such as
growth rate and drug tolerance. Metabolic specialization is believed to be a cause of such …

When conditions change, unicellular organisms rewire their metabolism to sustain cell
maintenance and cellular growth. Such rewiring may be understood as resource re …

Bacterial fitness depends on adaptability to changing environments. In rich growth medium,
which is replete with amino acids, Escherichia coli primarily expresses protein synthesis …

Saccharomyces cerevisiae is a widely used cell factory; therefore, it is important to
understand how it organizes key functional parts when cultured under different conditions …

Genomes produce widespread long non-coding RNAs (lncRNAs) of largely unknown
functions. We characterize aal1 (ageing-associated lncRNA), which is induced in quiescent …

Microorganisms release abundant volatile organic compounds, and these compounds have
important roles in distant interactions and communication. However, the effects of microbial …