Regulated cell death (RCD) triggered by innate immune activation is an important strategy
for host survival during pathogen invasion and perturbations of cellular homeostasis. There …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), is a major global health
issue, with around 10 million new cases annually. Advances in TB immunology have …

Tuberculosis (TB) is a global health problem of major concern. Identification of immune
biomarkers may facilitate the early diagnosis and targeted treatment of TB. We used public …

Abstract AIM2 (absent in melanoma 2), an inflammasome component, mediates IL-1β
release in murine macrophages and cell lines. AIM2 and IL-1β contribute to murine control …

COVID‐19 has a broad spectrum of clinical manifestations, from asymptomatic or
mild/moderate symptoms to severe symptoms and death. The mechanisms underlying its …

Background Numerous genetic variations in inflammasome components are linked to
prevalent disorders in the general population, including periodontitis and cardiovascular …

Inflammasomes comprise a group of protein complexes with fundamental roles in the
induction of inflammation. Upon sensing stress factors, their assembly induces the activation …

Background Tuberculosis is a serious life-threatening disease among the top global health
challenges and rapid and effective diagnostic biomarkers are vital for early diagnosis …

Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tb), is
responsible for> 1.5 million deaths worldwide annually. Innate immune cells, especially …

The present study was performed to evaluate the association of WNT signaling pathway
genes variants with pulmonary tuberculosis (PTB) risk in Chinese Han population. Our study …