Aldo-keto reductases (AKRs) are promiscuous NAD (P)(H) dependent oxidoreductases
implicated in the metabolic activation of polycyclic aromatic hydrocarbons (PAH). These …

Structurally modified polycyclic aromatic hydrocarbons (PAHs) such as nitrated PAHs (nitro-
PAHs) and oxygenated PAHs (oxy-PAHs) can be incriminated in the total toxicity of …

Quinones represent a class of toxicological intermediates, which can create a variety of
hazardous effects in vivo including, acute cytotoxicity, immunotoxicity, and carcinogenesis …

Abstract N-(1, 3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) as a rubber
antioxidant has attracted global concern, since its ozone-oxidation product 6PPD-quinone …

Worldwide, cancers of the oral cavity and pharynx comprise the sixth most common
malignancies. Histologically, more than 90% of oral cancers are squamous cell carcinoma …

Air pollutants include many compounds among them oxygenated polycyclic aromatic
hydrocarbons (oxy‐PAHs). As they are suspected to generate DNA damage and …

The formation of DNA adducts by genotoxic agents is an early event in cancer development,
and it may lead to gene mutations, thereby initiating tumor development. The measurement …

Self‐assembly of block copolymers has recently drawn great attention due to its remarkable
performance and wide variety of applications in biomedicine, biomaterials, microelectronics …

Abstract Benzo [a] pyrene (BaP) is an environmental pollutant that, based on evidence
largely from in vitro studies, exerts its genotoxic effects after metabolic activation by …

DNA adducts in fish represent a very important genotoxicity endpoint in environmental
monitoring, being a pre-mutagenic lesion that plays an essential role in the initiation of …