The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in
providing tools and technologies for antiviral research and treatment development. In this …

The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

Mast cells are important effector cells of the immune system and recent studies show that
they have immunomodulatory roles in diverse processes in both health and disease. Mast …

In cancer patients, visual identification of sentinel lymph nodes (LNs) is achieved by the
injection of dyes that bind avidly to endogenous albumin, targeting these compounds to LNs …

Pancreatic cancer is one of the most lethal malignancies worldwide. Although the standard
of care in pancreatic cancer has improved, prognoses for patients remain poor with a 5-year …

Implanting materials in the body to program host immune cells is a promising alternative to
transplantation of cells manipulated ex vivo to direct an immune response, but doing so …

Mast cells (MCs) influence intercellular communication during inflammation by secreting
cytoplasmic granules that contain diverse mediators. Here, we have demonstrated that MCs …

Vaccines aim to protect against or treat diseases through manipulation of the immune
response, promoting either immunity or tolerance. In the former case, vaccines generate …

A major challenge in vaccine formulations is the stimulation of both the humoral and cellular
immune response for well-defined antigens with high efficacy and safety. Adjuvant research …