Nanotechnological strategies for systemic microbial infections treatment: A review

MA dos Santos Ramos, KC Dos Santos… - International Journal of …, 2020 - Elsevier
Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug
approaches applied for the rapid and necessary treatment contribute to increase the levels …

Characteristics, Biological Properties and Analytical Methods of Trans-Resveratrol: A Review

BV Fiod Riccio, B Fonseca-Santos… - Critical Reviews in …, 2020 - Taylor & Francis
Trans-resveratrol (TR) is the biological active isomer of resveratrol and the one responsible
for therapeutic effects; both molecules are non-flavonoid phenolics of the stilbenes class …

Interventions for American cutaneous and mucocutaneous leishmaniasis

M Pinart, JR Rueda, GAS Romero… - Cochrane Database …, 2020 - cochranelibrary.com
Background On the American continent, cutaneous and mucocutaneous leishmaniasis (CL
and MCL) are diseases associated with infection by several species of Leishmania …

A curcumin-loaded liquid crystal precursor mucoadhesive system for the treatment of vaginal candidiasis

R Salmazi, G Calixto, J Bernegossi… - International Journal …, 2015 - Taylor & Francis
Women often develop vaginal infections that are caused primarily by organisms of the genus
Candida. The current treatments of vaginal candidiasis usually involve azole-based …

Clotrimazole loaded ufosomes for topical delivery: Formulation development and in-vitro studies

PK Bolla, CA Meraz, VA Rodriguez, I Deaguero… - Molecules, 2019 - mdpi.com
Global incidence of superficial fungal infections caused by dermatophytes is high and affects
around 40 million people. It is the fourth most common cause of infection. Clotrimazole, a …

Design and characterization of lipid-surfactant-based systems for enhancing topical anti-inflammatory activity of ursolic acid

B Fonseca-Santos, GA Araujo, PS Ferreira… - Pharmaceutics, 2023 - mdpi.com
Skin inflammation is a symptom of many skin diseases, such as eczema, psoriasis, and
dermatitis, which cause rashes, redness, heat, or blistering. The use of natural products with …

Antimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries

KL Aida, PF Kreling, KS Caiaffa… - International Journal …, 2018 - Taylor & Francis
Background Anticaries agents must interfere with the adhesion of Streptococcus mutans and
its proliferation in dental biofilm, without causing host toxicity and bacterial resistance …

Curcumin-loaded Polyethyleneimine and chitosan polymer-based Mucoadhesive liquid crystalline systems as a potential platform in the treatment of cervical Cancer

FD Victorelli, GMF Calixto, KC dos Santos… - Journal of Molecular …, 2021 - Elsevier
Cervical cancer is the fourth most common cancer in women. Conventional treatments
involve surgery, radiotherapy and radiochemotherapy, which affect negatively the life …

Amyloid fibrils enhance the topical bio‐adhesivity of liquid crystalline mesophase‐based drug formulations

FD Victorelli, CF Rodero, V Lutz‐Bueno… - Advanced …, 2023 - Wiley Online Library
Despite their distinctive secondary structure based on cross β‐strands, amyloid fibrils (AF)
are stable fibrous protein aggregates with features similar to collagen, one of the main …

Photodynamic potential of curcumin in bioadhesive formulations: Optical characteristics and antimicrobial effect against biofilms

C Santezi, BD Reina, SR de Annunzio, G Calixto… - Photodiagnosis and …, 2021 - Elsevier
Abstract Background: Although Curcumin (CUR) has great potential as a photosensitizer,
the low solubility in water impairs its clinical performance in photodynamic inactivation (PDI) …