C Riccardi, E Napolitano, C Platella… - Pharmacology & …, 2021 - Elsevier
First studies on thrombin-inhibiting DNA aptamers were reported in 1992, and since then a large number of anticoagulant aptamers has been discovered. TBA–also named HD1, a 15 …
A Proust, CJ Queval, R Harvey, L Adams… - Journal of …, 2023 - Springer
Background Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus …
Y Ma, KS Yang, ZZ Geng, YR Alugubelli… - European Journal of …, 2022 - Elsevier
As an essential enzyme of SARS-CoV-2, the COVID-19 pathogen, main protease (M Pro) is a viable target to develop antivirals for the treatment of COVID-19. By varying chemical …
D Trucco, L Vannozzi, E Teblum… - Advanced …, 2021 - Wiley Online Library
Articular cartilage (AC) is a specialized connective tissue able to provide a low‐friction gliding surface supporting shock‐absorption, reducing stresses, and guaranteeing wear …
P Das, T Dutta, S Manna, S Loganathan… - Environmental Research, 2022 - Elsevier
Since the last few decades, the green synthesis of metal nanoparticles was one of the most thrust areas due to its widespread application. The study proposed using wasted and …
The development of novel therapeutic approaches with high efficiency and precision like photothermal therapy (PTT) is essential to combat breast cancer. The gold nanoparticle …
Boceprevir is an HCV NSP3 inhibitor that was explored as a repurposed drug for COVID-19. It inhibits the SARS-CoV-2 main protease (M Pro) and contains an α-ketoamide warhead, a …
AC Puhl, EJ Fritch, TR Lane, LV Tse, BL Yount… - ACS …, 2021 - ACS Publications
Severe acute respiratory coronavirus 2 (SARS-CoV-2) is a newly identified virus that has resulted in over 2.5 million deaths globally and over 116 million cases globally in March …
J Zhang, A Rakhimbekova, X Duan, Q Yin… - Nature …, 2021 - nature.com
Surgery is an efficient way to treat localized prostate cancer (PCa), however, it is challenging to demarcate rapidly and accurately the tumor boundary intraoperatively, as existing tumor …