Ischemia, immunosuppression and infection—tackling the predicaments of post-stroke complications

R Shim, CHY Wong - International journal of molecular sciences, 2016 - mdpi.com
The incidence of stroke has risen over the past decade and will continue to be one of the
leading causes of death and disability worldwide. While a large portion of immediate death …

Neuro-immune hemostasis: homeostasis and diseases in the central nervous system

C De Luca, AM Colangelo, L Alberghina… - Frontiers in cellular …, 2018 - frontiersin.org
Coagulation and the immune system interact in several physiological and pathological
conditions, including tissue repair, host defense, and homeostatic maintenance. This …

Leukocyte recruitment and ischemic brain injury

G Yilmaz, DN Granger - Neuromolecular medicine, 2010 - Springer
Leukocytes are recruited into the cerebral microcirculation following an ischemic insult. The
leukocyte–endothelial cell adhesion manifested within a few hours after ischemia (followed …

Importance of T lymphocytes in brain injury, immunodeficiency, and recovery after cerebral ischemia

VH Brait, TV Arumugam… - Journal of Cerebral …, 2012 - journals.sagepub.com
Following an ischemic stroke, T lymphocytes become activated, infiltrate the brain, and
appear to release cytokines and reactive oxygen species to contribute to early inflammation …

New insights into the roles of microglial regulation in brain plasticity-dependent stroke recovery

F Yu, T Huang, Y Ran, D Li, L Ye, G Tian… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke remains the leading cause of long-term disability worldwide with significant long-term
sequelae. However, there is no highly effective treatment to enhance post-stroke recovery …

Inflammatory signalling associated with brain dead organ donation: from brain injury to brain stem death and posttransplant ischaemia reperfusion injury

RP Watts, O Thom, JF Fraser - Journal of transplantation, 2013 - Wiley Online Library
Brain death is associated with dramatic and serious pathophysiologic changes that
adversely affect both the quantity and quality of organs available for transplant. To fully …

[HTML][HTML] Imbalance of Th1/Th2 and Th17/Treg during the development of uterine cervical cancer

W Lin, Z Niu, H Zhang, Y Kong, Z Wang… - … journal of clinical and …, 2019 - ncbi.nlm.nih.gov
Uterine cervical cancer (UCC) causes more than one quarter of a million deaths per year in
many developing countries. Nearly all cases of cervical cancer result from infection with the …

Neuroinflammatory triangle presenting novel pharmacological targets for ischemic brain injury

ZA Shaheryar, MA Khan, CS Adnan, AA Zaidi… - Frontiers in …, 2021 - frontiersin.org
Ischemic stroke is one of the leading causes of morbidity and mortality globally. Hundreds of
clinical trials have proven ineffective in bringing forth a definitive and effective treatment for …

Activation of T lymphocytes in atherosclerotic plaques

JC Grivel, O Ivanova, N Pinegina, PS Blank… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—To decipher the immunologic mechanisms of plaque maturation and rupture, it is
necessary to analyze the phenotypes and distribution of individual lymphocytes that migrate …

Longitudinal change of Th1, Th2, and Th17 cells and their relationship between cognitive impairment, stroke recurrence, and mortality among acute ischemic stroke …

S Yu, W Cui, J Han, J Chen… - Journal of Clinical …, 2022 - Wiley Online Library
Background T‐helper (Th) cells regulate immunity and inflammation, and modulate cognitive
impairment in both cardio‐cerebrovascular and neurological diseases. This study aimed to …