Natural killer (NK) cells provide protection against infectious pathogens and cancer. For
decades it has been appreciated that two major NK cell subsets (CD56 bright and CD56 …

Natural killer (NK) cell‐mediated cytotoxicity is governed by the formation of a lytic immune
synapse in discrete regulated steps, which give rise to an extensive array of cellular …

According to in vitro assays, T cells are thought to kill rapidly and efficiently, but the efficacy
and dynamics of cytotoxic T lymphocyte (CTL)-mediated killing of virus-infected cells in vivo …

Natural Killer (NK) cells are a type of innate lymphoid cells that play a crucial role in
immunity by killing virally infected or tumor cells and secreting cytokines and chemokines …

Triple negative breast cancers (TNBC) remain a major medical challenge due to poor
prognosis and limited treatment options. Mesothelin is a glycosyl-phosphatidyl inositol …

IFN-γ is a pathogenic cytokine involved in inflammation. Paradoxically, its deficiency
exacerbates experimental autoimmune encephalomyelitis, uveitis, and arthritis. Here, we …

Vaccines represent one of the major advances of modern medicine. Despite the many
successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” …

Cytotoxic T cells (CTLs) can eliminate tumor cells through the delivery of lethal hits, but the
actual efficiency of this process in the tumor microenvironment is unclear. Here, we …

Dendritic cells (DCs) act as a bridge between innate and adoptive immunity. They are widely
distributed in various tissues and organs. Resident ocular DCs are found in the peripheral …

The migration of immune cells plays a key role in inflammation. This is evident in the fact that
inflammatory stimuli elicit a broad range of migration patterns in immune cells. Since these …