Fluorescence imaging of large-scale neural ensemble dynamics

TH Kim, MJ Schnitzer - Cell, 2022 - cell.com
Recent progress in fluorescence imaging allows neuroscientists to observe the dynamics of
thousands of individual neurons, identified genetically or by their connectivity, across …

Wide-field calcium imaging of neuronal network dynamics in vivo

AK Nietz, LS Popa, ML Streng, RE Carter… - Biology, 2022 - mdpi.com
Simple Summary We review advances in the properties of calcium sensors, microscopy, and
data analysis that have brought about the ability to image large contiguous regions of the …

Miniscope-LFOV: a large-field-of-view, single-cell-resolution, miniature microscope for wired and wire-free imaging of neural dynamics in freely behaving animals

C Guo, GJ Blair, M Sehgal, FN Sangiuliano Jimka… - Science …, 2023 - science.org
Imaging large-population, single-cell fluorescent dynamics in freely behaving animals larger
than mice remains a key endeavor of neuroscience. We present a large-field-of-view open …

Mesoscopic calcium imaging in a head-unrestrained male non-human primate using a lensless microscope

J Wu, Y Chen, A Veeraraghavan, E Seidemann… - Nature …, 2024 - nature.com
Mesoscopic calcium imaging enables studies of cell-type specific neural activity over large
areas. A growing body of literature suggests that neural activity can be different when …

Large-scale high-density brain-wide neural recording in nonhuman primates

EM Trautmann, JK Hesse, GM Stine, R Xia, S Zhu… - BioRxiv, 2023 - biorxiv.org
High-density, integrated silicon electrodes have begun to transform systems neuroscience,
by enabling large-scale neural population recordings with single cell resolution. Existing …

Neurobind: Towards unified multimodal representations for neural signals

F Yang, C Feng, D Wang, T Wang, Z Zeng, Z Xu… - arXiv preprint arXiv …, 2024 - arxiv.org
Understanding neural activity and information representation is crucial for advancing
knowledge of brain function and cognition. Neural activity, measured through techniques …

Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

EM Trautmann, DJ O'Shea, X Sun, JH Marshel… - Nature …, 2021 - nature.com
Calcium imaging is a powerful tool for recording from large populations of neurons in vivo.
Imaging in rhesus macaque motor cortex can enable the discovery of fundamental principles …

Miniature microscopes for manipulating and recording in vivo brain activity

AM Stamatakis, SL Resendez, KS Chen, M Favero… - …, 2021 - academic.oup.com
Here we describe the development and application of miniature integrated microscopes
(miniscopes) paired with microendoscopes that allow for the visualization and manipulation …

Dynamics of directional motor tuning in the primate premotor and primary motor cortices during sensorimotor learning

T Ebina, A Sasagawa, D Hong, R Setsuie… - Nature …, 2024 - nature.com
Sensorimotor learning requires reorganization of neuronal activity in the premotor cortex
(PM) and primary motor cortex (M1). To reveal PM-and M1-specific reorganization in a …

Spectral fiber photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activity

WT Zhang, THH Chao, Y Yang, TW Wang, SH Lee… - Cell reports …, 2022 - cell.com
Fiber photometry is an emerging technique for recording fluorescent sensor activity in the
brain. However, significant hemoglobin absorption artifacts in fiber photometry data may be …