Is the suppression of CD36 a promising way for atherosclerosis therapy?

SY Wen, X Zhi, HX Liu, X Wang, YY Chen… - Biochemical …, 2024 - Elsevier
Atherosclerosis is the main underlying pathology of many cardiovascular diseases and is
marked by plaque formation in the artery wall. It has posed a serious threat to the health of …

Reprogramming macrophage metabolism following myocardial infarction: A neglected piece of a therapeutic opportunity

B Xie, J Li, Y Lou, Q Chen, Y Yang, R Zhang… - International …, 2024 - Elsevier
Given the global prevalence of myocardial infarction (MI) as the leading cause of mortality,
there is an urgent need to devise novel strategies that target reducing infarct size …

[HTML][HTML] Bile Acid Metabolism Analysis Provides Insights into Vascular Endothelial Injury in Salt-Sensitive Hypertensive Rats

B Zeng, X Peng, L Chen, J Liu, L Xia - Metabolites, 2024 - mdpi.com
As an unhealthy dietary habit, a high-salt diet can affect the body's endocrine system and
metabolic processes. As one of the most important metabolites, bile acids can prevent …

Microglia nuclear receptor corepressor 1 deficiency alleviates neuroinflammation in mice

S Qiu, Z Xian, J Chen, P Huang, H Wang, H Wang… - Neuroscience …, 2024 - Elsevier
Given the established role of nuclear receptor corepressor 1 (NCoR1) in sensing
environmental cues and the importance of inflammation in neurodegenerative diseases …

Bile salt signaling and bile salt-based therapies in cardiometabolic disease

CCJ Groenen, TA Nguyen, CC Paulusma… - Clinical …, 2024 - portlandpress.com
Bile salts have an established role in the emulsification and intestinal absorption of dietary
lipids, and their homeostasis is tightly controlled by various transporters and regulators in …