Design, synthesis and anti-influenza virus activity of furan-substituted spirothiazolidinones

ÇB Apaydın, M Tansuyu, Z Cesur, L Naesens… - Bioorganic …, 2021 - Elsevier
A new series of N-(3-oxo-1-thia-4-azaspiro [4.5] decan-4-yl) carboxamides have been
designed, synthesized and evaluated as antiviral agents. The compounds were prepared by …

Design, synthesis, antitubercular and antiviral properties of new spirocyclic indole derivatives

G Cihan-Üstündağ, L Naesens, D Şatana… - Monatshefte für Chemie …, 2019 - Springer
A series of indole-based spirothiazolidinones have been designed, synthesized and
evaluated, in vitro, for their antitubercular, antiviral, antibacterial, and antifungal activities …

Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinones

G Cihan-Üstündağ, M Zopun, E Vanderlinden… - Bioorganic & medicinal …, 2020 - Elsevier
The influenza virus hemagglutinin (HA) mediates membrane fusion after viral entry by
endocytosis. The fusion process requires drastic low pH-induced HA refolding and is …

Synthesis and antibacterial activity of new hybrid derivatives of 5-sulfamoyl-1H-indole and 4-thiazolidinone groups

Ö Güzel-Akdemir, M Trawally, M Özbek-Babuç… - Monatshefte für Chemie …, 2020 - Springer
The synthesis of a series of new 3-phenyl-5-sulfamoyl-N-(7/8/9-(non) substituted-3-oxo-1-
thia-4-azaspiro [4.4] non/[4.5] dec-4-yl)-1 H-indole-2-carboxamide derivatives and their …

Synthesis of new N‐(3‐oxo‐1‐thia‐4‐azaspiro[4.5]decan‐4‐yl)pyridine‐3‐carboxamide derivatives and evaluation of their anti‐influenza virus and antitubercular …

G Cihan‑Üstündağ, Ç Acar, L Naesens… - Archiv der …, 2022 - Wiley Online Library
We here report the synthesis, structural characterization, and evaluation of the antiviral and
antitubercular activities of a novel series of hybrid spirothiazolidinone derivatives (2a–f and …

Synthesis, Characterization and Antiviral Activities of Some Novel 4-Thiazolidinones Derived from Imidazo [2, 1-b][1, 3] thiazole-5-carbohydrazide Hydrazones

M Isaoglu, N Cesur - Anatolian Journal of Biology, 2020 - dergipark.org.tr
The present study describes the synthesis, characterization and antiviral activity evaluation
of some novel 5-(nonsubstitue/methyl)-4-oxo-2-(substituted phenyl)-1, 3-thiazolidine-4-one …

New spirothiazolidinone derivatives: Synthesis and antiviral evaluation

ÇB Apaydın, BV Loy, A Stevaert… - Phosphorus, Sulfur, and …, 2020 - Taylor & Francis
A new series of N-(3-oxo-1-thia-4-azaspiro [4.5] decan-4-yl) carboxamide derivatives were
designed, synthesized, and evaluated for their antiviral activity. These new …

One-pot synthesis, characterization and antiviral properties of new benzenesulfonamide-based spirothiazolidinones

ÇB Apaydın, L Naesens, G Cihan-Üstündağ - Molecular Diversity, 2024 - Springer
A novel series of benzenesulfonamide substituted spirothiazolidinone derivatives (3a–j)
were synthesized, characterized and evaluated for their antiviral activity. The spirocyclic …

Diclofenac‐Based Hydrazones and Spirothiazolidinones: Synthesis, Characterization, and Antimicrobial Properties

A Kocabalkanlı, G Cihan‐Üstündağ… - Archiv der …, 2017 - Wiley Online Library
We report here the synthesis, structural characterization, and biological evaluation of novel
diclofenac‐based hydrazone (4a–f) and spirothiazolidinone (5a–f, 6a–f) derivatives …

Synthesis, in vitro cytotoxic and apoptotic effects, and molecular docking study of novel adamantane derivatives

B Turk‐Erbul, EF Karaman, GN Duran… - Archiv der …, 2021 - Wiley Online Library
(Adamantane‐1‐carboxamido)‐3‐oxo‐1‐thia‐4‐azaspiro [4.4] nonan‐2‐yl] acetic acid (4a)
and [4‐(adamantane‐1‐carboxamido)‐8‐nonsubstituted/substituted‐3‐oxo‐1‐thia‐4‐azas …