[HTML][HTML] Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae
RE Chen, J Thorner - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2007 - Elsevier
Signaling pathways that activate different mitogen-activated protein kinases (MAPKs) elicit
many of the responses that are evoked in cells by changes in certain environmental …
many of the responses that are evoked in cells by changes in certain environmental …
Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins
AC Magalhaes, H Dunn… - British journal of …, 2012 - Wiley Online Library
GPCRs represent the largest family of integral membrane proteins and were first identified
as receptor proteins that couple via heterotrimeric G‐proteins to regulate a vast variety of …
as receptor proteins that couple via heterotrimeric G‐proteins to regulate a vast variety of …
[HTML][HTML] DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
The mTORC1 and mTORC2 pathways regulate cell growth, proliferation, and survival. We
identify DEPTOR as an mTOR-interacting protein whose expression is negatively regulated …
identify DEPTOR as an mTOR-interacting protein whose expression is negatively regulated …
Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex
GPR158 is an orphan G protein–coupled receptor (GPCR) highly expressed in the brain,
where it controls synapse formation and function. GPR158 has also been implicated in …
where it controls synapse formation and function. GPR158 has also been implicated in …
Wnt/β-catenin signaling requires interaction of the Dishevelled DEP domain and C terminus with a discontinuous motif in Frizzled
DVF Tauriello, I Jordens, K Kirchner… - Proceedings of the …, 2012 - National Acad Sciences
Wnt binding to members of the seven-span transmembrane Frizzled (Fz) receptor family
controls essential cell fate decisions and tissue polarity during development and in …
controls essential cell fate decisions and tissue polarity during development and in …
Role of the Wnt‐Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential
Abstract The Wnt‐Frizzled (Fzd) G‐protein‐coupled receptor system, involving 19 distinct
Wnt ligands and 10 Fzd receptors, plays key roles in the development and functioning of …
Wnt ligands and 10 Fzd receptors, plays key roles in the development and functioning of …
[HTML][HTML] A focus on yeast mating: From pheromone signaling to cell-cell fusion
Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …
Comparative genomics of MAP kinase and calcium–calcineurin signalling components in plant and human pathogenic fungi
N Rispail, DM Soanes, C Ant, R Czajkowski… - Fungal Genetics and …, 2009 - Elsevier
Mitogen-activated protein kinase (MAPK) cascades and the calcium–calcineurin pathway
control fundamental aspects of fungal growth, development and reproduction. Core …
control fundamental aspects of fungal growth, development and reproduction. Core …
Structure of the class C orphan GPCR GPR158 in complex with RGS7-Gβ5
E Jeong, Y Kim, J Jeong, Y Cho - Nature communications, 2021 - nature.com
GPR158, a class C orphan GPCR, functions in cognition, stress-induced mood control, and
synaptic development. Among class C GPCRs, GPR158 is unique as it lacks a Venus flytrap …
synaptic development. Among class C GPCRs, GPR158 is unique as it lacks a Venus flytrap …
Negative feedback that improves information transmission in yeast signalling
Haploid Saccharomyces cerevisiae yeast cells use a prototypic cell signalling system to
transmit information about the extracellular concentration of mating pheromone secreted by …
transmit information about the extracellular concentration of mating pheromone secreted by …