Psoriatic arthritis: pathogenesis and targeted therapies

AB Azuaga, J Ramírez, JD Cañete - International journal of molecular …, 2023 - mdpi.com
Psoriatic arthritis (PsA), a heterogeneous chronic inflammatory immune-mediated disease
characterized by musculoskeletal inflammation (arthritis, enthesitis, spondylitis, and …

Current research topics in FAPI theranostics: a bibliometric analysis

AF van den Hoven, RGM Keijsers, MGEH Lam… - European Journal of …, 2023 - Springer
Purpose The study aimed to provide a comprehensive bibliometric overview of the current
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …

Bispecific T cell engager therapy for refractory rheumatoid arthritis

L Bucci, M Hagen, T Rothe, MG Raimondo, F Fagni… - Nature Medicine, 2024 - nature.com
Bispecific T cell engagers (BiTEs) kill B cells by engaging T cells. BiTEs are highly effective
in acute lymphoblastic leukemia. Here we treated six patients with multidrug-resistant …

CD200+ fibroblasts form a pro-resolving mesenchymal network in arthritis

S Rauber, H Mohammadian, C Schmidkonz… - Nature …, 2024 - nature.com
Fibroblasts are important regulators of inflammation, but whether fibroblasts change
phenotype during resolution of inflammation is not clear. Here we use positron emission …

Imaging in inflammatory arthritis: progress towards precision medicine

I Minopoulou, A Kleyer, M Yalcin-Mutlu… - Nature Reviews …, 2023 - nature.com
Imaging techniques such as ultrasonography and MRI have gained ground in the diagnosis
and management of inflammatory arthritis, as these imaging modalities allow a sensitive …

[68Ga]Ga-FAPI-04 PET/CT on assessing Crohn's disease intestinal lesions

L Chen, X Zhong, L Li, X Li, Y Liu, C Guo… - European Journal of …, 2023 - Springer
Background Fibrosis and inflammation are major pathological changes of Crohn's disease
(CD). Early detection and accurate severity evaluation of CD are critical for patient's …

Unconventional Imaging Methods in Psoriatic Arthritis

I Minopoulou, F Fagni, A Atzinger, F Albach… - Current Rheumatology …, 2025 - Springer
Abstract Purpose of Review Psoriatic arthritis (PsA) is a complex heterogeneous
inflammatory disease that affects about one-third of patients with psoriasis. PsA leads to …

1,090 Publications and 5 Years Later: Is FAP-Targeted Theranostics Really Happening?

U Haberkorn, A Altmann, FL Giesel… - Journal of Nuclear …, 2024 - jnm.snmjournals.org
Tumors consist of not only malignant cells but also stroma cells which include vascular and
inflammatory cells and activated fibroblasts and may contribute up to more than 90% of the …

Fibroblast activation protein inhibitor imaging in nonmalignant diseases: a new perspective for molecular imaging

C Schmidkonz, T Kuwert, A Atzinger… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Fibroblast activation protein-α (FAP-α) is a type II transmembrane glycoprotein that is
overexpressed in activated fibroblasts such as those in the stroma of tumors or in the fibrotic …

Emerging role of FAPI PET imaging for the assessment of benign bone and joint diseases

F Dondi, D Albano, G Treglia, F Bertagna - Journal of clinical medicine, 2022 - mdpi.com
Positron emission tomography/computed tomography (PET/CT) is a hybrid imaging modality
that has recently experienced a wide increase in its use and applications. The most common …