[HTML][HTML] Promising effects of emoxypine and its succinate derivative in the management of various diseases-with insights on recent patent applications
Emoxypine and its succinate derivative share a common hydroxypridine structure, which is
similar to pyridoxine. These compounds have been utilized therapeutically and industrially …
similar to pyridoxine. These compounds have been utilized therapeutically and industrially …
Spatial structure, thermodynamics and kinetics of formation of hydrazones derived from pyridoxal 5′-phosphate and 2-furoic, thiophene-2-carboxylic hydrazides in …
The spatial structure of pyridoxal 5′-phosphate hydrazones of 2-furoic hydrazide;
thiophene-2-carboxylic hydrazide in aqueous solution was studied by means of quantum …
thiophene-2-carboxylic hydrazide in aqueous solution was studied by means of quantum …
A combined experimental and theoretical study of miconazole salts and cocrystals: Crystal structures, DFT computations, formation thermodynamics and solubility …
Experimental and theoretical screening of multi-component crystal forms of miconazole
(MCL), an antifungal drug, with ten aliphatic dicarboxylic acids was performed. Seven multi …
(MCL), an antifungal drug, with ten aliphatic dicarboxylic acids was performed. Seven multi …
Two faces of water in the formation and stabilization of multicomponent crystals of zwitterionic drug-like compounds
AO Surov, NA Vasilev, AV Churakov, OD Parashchuk… - Symmetry, 2021 - mdpi.com
Two new hydrated multicomponent crystals of zwitterionic 2-aminonicotinic acid with maleic
and fumaric acids have been obtained and thoroughly characterized by a variety of …
and fumaric acids have been obtained and thoroughly characterized by a variety of …
Combined X-ray Crystallographic, IR/Raman Spectroscopic, and Periodic DFT Investigations of New Multicomponent Crystalline Forms of Anthelmintic Drugs: A Case …
AP Voronin, AO Surov, AV Churakov, OD Parashchuk… - Molecules, 2020 - mdpi.com
Synthesis of multicomponent solid forms is an important method of modifying and fine-tuning
the most critical physicochemical properties of drug compounds. The design of new …
the most critical physicochemical properties of drug compounds. The design of new …
Structural and property analysis of three novel pharmaceutical salt solvates synthesized from paliperidone and aromatic carboxylic acids
J Chen, Z Shen, Z Cai, J Ge, XN Hua, K Sun… - Journal of Molecular …, 2024 - Elsevier
Paliperidone (PLPT) is a pharmaceutical compound widely used in the treatment of
psychiatric disorders. However, its limited solubility poses challenges for its formulation and …
psychiatric disorders. However, its limited solubility poses challenges for its formulation and …
Influence of co-amorphization on the physical stability and dissolution performance of an anthelmintic drug flubendazole
In this work, the co-amorphization approach was applied to flubendazole (FluBZ), resulting
in the formation of two novel solid forms of FluBZ with l-phenylalanine (Phe) and l-tryptophan …
in the formation of two novel solid forms of FluBZ with l-phenylalanine (Phe) and l-tryptophan …
New Solid Forms of Nitrofurantoin and 4-Aminopyridine Salt: Influence of Salt Hydration Level on Crystal Packing and Physicochemical Properties
The crystallization of the poorly soluble drug nitrofurantoin (NFT) with 4-aminopyridine
(4AmPy) resulted in three multicomponent solid forms with different hydration levels …
(4AmPy) resulted in three multicomponent solid forms with different hydration levels …
[PDF][PDF] Crystal structure of a 1: 1 salt of 4-aminobenzoic acid (vitamin B10) with pyrazinoic acid
KV Drozd, SG Arkhipov, EV Boldyreva… - Acta Crystallographica …, 2018 - journals.iucr.org
The title 1: 1 salt, C7H8NO2+· C5H3N2O2−(systematic name: 4-carboxyanilinium pyrazine-
2-carboxylate), was synthesized successfully by slow evaporation of a saturated solution …
2-carboxylate), was synthesized successfully by slow evaporation of a saturated solution …
Comparative analysis of experimental methods for determining thermodynamic parameters of formation of multi-component molecular crystals: Benefits and limitations
In this work, we have studied the processes of dissolution of 4-aminobenzoic acid (PABA)
two-component crystals with 6-methyluracil (6-MeUr), pyrazinamide (PyrAm) and emoxypine …
two-component crystals with 6-methyluracil (6-MeUr), pyrazinamide (PyrAm) and emoxypine …