CD146, from a melanoma cell adhesion molecule to a signaling receptor

Z Wang, Q Xu, N Zhang, X Du, G Xu… - Signal transduction and …, 2020 - nature.com
CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

An overview of the immune system

J Parkin, B Cohen - The Lancet, 2001 - thelancet.com
We are continually exposed to organisms that are inhaled, swallowed, or inhabit our skin
and mucous membranes. Whether these organisms penetrate and cause disease is a result …

Role of integrins in cell invasion and migration

JD Hood, DA Cheresh - Nature Reviews Cancer, 2002 - nature.com
As cancer cells undergo metastasis—invasion and migration of a new tissue—they
penetrate and attach to the target tissue's basal matrix. This allows the cancer cell to pull …

Anoikis mechanisms

SM Frisch, RA Screaton - Current opinion in cell biology, 2001 - Elsevier
Anoikis is defined as apoptosis that is induced by inadequate or inappropriate cell–matrix
interactions. It is involved in a wide diversity of tissue-homeostatic, developmental and …

Function and interactions of integrins

A Van der Flier, A Sonnenberg - Cell and tissue research, 2001 - Springer
Integrins are heterodimeric cell adhesion molecules that link the extracellular matrix to the
cytoskeleton. The integrin family in man comprises 24 members, which are the result of …

Behaviors of NIH-3T3 fibroblasts on graphene/carbon nanotubes: proliferation, focal adhesion, and gene transfection studies

SR Ryoo, YK Kim, MH Kim, DH Min - ACS nano, 2010 - ACS Publications
Carbon-based materials, including graphene and carbon nanotubes, have been considered
attractive candidates for biomedical applications such as scaffolds in tissue engineering …

An introductory review of cell mechanobiology

JHC Wang, BP Thampatty - Biomechanics and modeling in …, 2006 - Springer
Mechanical loads induce changes in the structure, composition, and function of living
tissues. Cells in tissues are responsible for these changes, which cause physiological or …

Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks

S Huang, DE Ingber - Experimental cell research, 2000 - Elsevier
Development of characteristic tissue patterns requires that individual cells be switched
locally between different phenotypes or “fates;” while one cell may proliferate, its neighbors …

Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members

RL Juliano - Annual review of pharmacology and toxicology, 2002 - annualreviews.org
Cellular interactions with the extracellular matrix and with neighboring cells profoundly
influence a variety of signaling events including those involved in mitogenesis, survival, and …

Establishing criteria for human mesenchymal stem cell potency

RM Samsonraj, B Rai, P Sathiyanathan, KJ Puan… - Stem …, 2015 - academic.oup.com
This study sought to identify critical determinants of mesenchymal stem cell (MSC) potency
using in vitro and in vivo attributes of cells isolated from the bone marrow of age‐and sex …