M Pohanka - International journal of molecular sciences, 2014 - mdpi.com
Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of Alzheimer's disease and other dementias. More recent use is for myasthenia gravis. Many of …
Over the past three decades, there has been constant postulation regarding the infectious etiology of Alzheimer disease (AD), which in turn suggests the vital role of various infectious …
Introduction Over three years have passed since the emergence of coronavirus disease 2019 (COVID-19), and yet the treatment for long-COVID, a post-COVID-19 syndrome …
J Hwang, H Hwang, HW Lee, K Suk - Neuropharmacology, 2010 - Elsevier
Donepezil is a reversible and noncompetitive cholinesterase inhibitor. The drug is considered as a first-line treatment in patients with mild to moderate Alzheimer's disease …
We sought a new approach to treating infections by intracellular bacteria, namely, by altering host cell functions that support their growth. We screened a library of 640 Food and Drug …
T Chen, R Hou, S Xu, C Wu - ACS Chemical Neuroscience, 2015 - ACS Publications
1-Methyl-4-phenylpyridinium (MPP+) induces microglial activation and degeneration of dopaminergic (DAergic) neurons. Donepezil is a well-known acetylcholinesterase inhibitor …
P Pooladgar, M Sakhabakhsh, A Taghva… - Iranian Journal of …, 2022 - ncbi.nlm.nih.gov
Donepezil hydrochloride is an acetylcholine esterase inhibitor studied and approved to treat Alzheimer's disease (AD). However, this drug can have positive therapeutic potential in …
Z Blach-Olszewska, E Zaczynska… - Current …, 2015 - benthamdirect.com
The genetic, cellular, and molecular changes associated with Alzheimer disease provide evidence of immune and inflammatory processes involvement in its pathogenesis. These …
M Sochocka, E Zaczyńska, A Taboł, A Czarny… - International …, 2010 - Elsevier
Ginkgo biloba special extract EGb 761 and donepezil are drugs used in Alzheimer therapy. The influence of donepezil and EGb 761 on two mechanisms of innate immunity, natural …