Drug delivery applications of core-sheath nanofibers prepared by coaxial electrospinning: a review

B Pant, M Park, SJ Park - Pharmaceutics, 2019 - mdpi.com
Electrospinning has emerged as one of the potential techniques for producing nanofibers.
The use of electrospun nanofibers in drug delivery has increased rapidly over recent years …

Bioactive electrospun scaffolds delivering growth factors and genes for tissue engineering applications

W Ji, Y Sun, F Yang, JJJP van den Beucken… - Pharmaceutical …, 2011 - Springer
ABSTRACT A biomaterial scaffold is one of the key factors for successful tissue engineering.
In recent years, an increasing tendency has been observed toward the combination of …

Current approaches to electrospun nanofibers for tissue engineering

NG Rim, CS Shin, H Shin - Biomedical materials, 2013 - iopscience.iop.org
The ultimate goal of tissue engineering is to replace damaged tissues by applying
engineering technology and the principles of life sciences. To successfully engineer a …

Mineralized nanofiber segments coupled with calcium-binding BMP-2 peptides for alveolar bone regeneration

SK Boda, Y Almoshari, H Wang, X Wang… - Acta Biomaterialia, 2019 - Elsevier
Bone loss around tooth extraction sites can occur, thus making future placement of dental
implants difficult. Alveolar bone regeneration can be guided by the application of a …

Coaxial electrospinning for encapsulation and controlled release of fragile water-soluble bioactive agents

H Jiang, L Wang, K Zhu - Journal of Controlled Release, 2014 - Elsevier
Coaxial electrospinning is a robust technique for one-step encapsulation of fragile, water-
soluble bioactive agents, including growth factors, DNA and even living organisms, into core …

Dual-delivery of VEGF and PDGF by double-layered electrospun membranes for blood vessel regeneration

H Zhang, X Jia, F Han, J Zhao, Y Zhao, Y Fan, X Yuan - Biomaterials, 2013 - Elsevier
Tissue engineering of small-diameter blood vessels is still challenging because of
restenosis and burst. To prevent thrombosis, rapid endothelialization along the lumen of …

Electrospun cellular microenvironments: Understanding controlled release and scaffold structure

A Szentivanyi, T Chakradeo, H Zernetsch… - Advanced drug delivery …, 2011 - Elsevier
Electrospinning is a versatile technique in tissue engineering for the production of scaffolds.
To guide tissue development, scaffolds must provide specific biochemical, structural and …

Core–shell designed scaffolds for drug delivery and tissue engineering

RA Perez, HW Kim - Acta biomaterialia, 2015 - Elsevier
Scaffolds that secure and deliver therapeutic ingredients like signaling molecules and stem
cells hold great promise for drug delivery and tissue engineering. Employing a core–shell …

Vascularization strategies for skin tissue engineering

A Amirsadeghi, A Jafari, LJ Eggermont… - Biomaterials …, 2020 - pubs.rsc.org
A number of challenges in skin grafting for wound healing have drawn researchers to focus
on skin tissue engineering as an alternative solution. The core idea of tissue engineering is …

Novel strategies for the formulation and processing of poorly water-soluble drugs

K Göke, T Lorenz, A Repanas, F Schneider… - European Journal of …, 2018 - Elsevier
Low aqueous solubility of active pharmaceutical ingredients presents a serious challenge in
the development process of new drug products. This article provides an overview on some …