Peripheral mechanisms of chronic pain

Q Zheng, X Dong, DP Green, X Dong - Medical Review, 2022 - degruyter.com
Acutely, pain serves to protect us from potentially harmful stimuli, however damage to the
somatosensory system can cause maladaptive changes in neurons leading to chronic pain …

Motor innervation directs the correct development of the mouse sympathetic nervous system

AG Erickson, A Motta, ME Kastriti, S Edwards… - Nature …, 2024 - nature.com
The sympathetic nervous system controls bodily functions including vascular tone, cardiac
rhythm, and the “fight-or-flight response”. Sympathetic chain ganglia develop in parallel with …

[HTML][HTML] Sprouting sympathetic fibres release CXCL16 and norepinephrine to synergistically mediate sensory neuronal hyperexcitability in a rodent model of …

C Wang, A Di, Y Wu, M Liu, M Wei, Z Liang, F Liu… - British Journal of …, 2025 - Elsevier
Background Chronic neuropathic pain generally has a poor response to treatment with
conventional drugs. Sympathectomy can alleviate neuropathic pain in some patients …

[PDF][PDF] Effect of Sympathetic Nerveon Neuropathic Spontaneous Pain

Z Hongfang, Y Haojun, L Jing - Acta Medicinae Universitatis …, 2024 - tjqk.magtech.com.cn
自发痛 (spontaneouspain) 是在没有明显外界刺激诱发的情况下存在的疼痛,
是神经病理性痛的主要临床表现之一, 其发病机制复杂, 目前缺乏有效的治疗手段 …