Understanding COVID-19-associated coagulopathy
EM Conway, N Mackman, RQ Warren… - Nature Reviews …, 2022 - nature.com
Abstract COVID-19-associated coagulopathy (CAC) is a life-threatening complication of
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
SARS-CoV-2 infection. However, the underlying cellular and molecular mechanisms driving …
Defining the risk of SARS-CoV-2 variants on immune protection
The global emergence of many severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
CoV-2) variants jeopardizes the protective antiviral immunity induced after infection or …
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …
from protection by vaccines and therapeutic antibodies. A key test for potential …
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA. 2
R Uraki, M Kiso, S Iida, M Imai, E Takashita, M Kuroda… - Nature, 2022 - nature.com
The recent emergence of SARS-CoV-2 Omicron (B. 1.1. 529 lineage) variants possessing
numerous mutations has raised concerns of decreased effectiveness of current vaccines …
numerous mutations has raised concerns of decreased effectiveness of current vaccines …
[PDF][PDF] The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry
TP Peacock, JC Brown, J Zhou, N Thakur… - …, 2022 - pdfs.semanticscholar.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models
Emergence of SARS-CoV-2 variants of concern (VOCs), including the highly transmissible
Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines …
Omicron and Delta strains, has posed constant challenges to the current COVID-19 vaccines …
The altered entry pathway and antigenic distance of the SARS-CoV-2 Omicron variant map to separate domains of spike protein
TP Peacock, JC Brown, J Zhou, N Thakur, K Sukhova… - biorxiv, 2022 - biorxiv.org
At the end of 2021 a new SARS-CoV-2 variant, Omicron, emerged and quickly spread
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
across the world. It has been demonstrated that Omicron's high number of Spike mutations …
[HTML][HTML] The SARS-CoV-2 B. 1.1. 529 Omicron virus causes attenuated infection and disease in mice and hamsters
M Diamond, P Halfmann, T Maemura… - Research …, 2021 - ncbi.nlm.nih.gov
Despite the development and deployment of antibody and vaccine countermeasures, rapidly-
spreading SARS-CoV-2 variants with mutations at key antigenic sites in the spike protein …
spreading SARS-CoV-2 variants with mutations at key antigenic sites in the spike protein …
Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants
Resistance represents a major challenge for antibody-based therapy for COVID-19,,–. Here
we engineered an immunoglobulin M (IgM) neutralizing antibody (IgM-14) to overcome the …
we engineered an immunoglobulin M (IgM) neutralizing antibody (IgM-14) to overcome the …
Animal models for COVID-19: advances, gaps and perspectives
C Fan, Y Wu, X Rui, Y Yang, C Ling, S Liu… - Signal transduction and …, 2022 - nature.com
Abstract COVID-19, caused by SARS-CoV-2, is the most consequential pandemic of this
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …
century. Since the outbreak in late 2019, animal models have been playing crucial roles in …