Oxidative Stress: A Culprit in the Progression of Diabetic Kidney Disease

N Wang, C Zhang - Antioxidants, 2024 - mdpi.com
Diabetic kidney disease (DKD) is the principal culprit behind chronic kidney disease (CKD),
ultimately developing end-stage renal disease (ESRD) and necessitating costly dialysis or …

Effects of xenogeneic transplantation of umbilical cord-derived mesenchymal stem cells combined with irbesartan on renal podocyte damage in diabetic rats

J Meng, X Gao, X Liu, W Zheng, Y Wang… - Stem Cell Research & …, 2024 - Springer
Background The leading cause of end-stage renal disease (ESRD) is diabetic nephropathy
(DN). Podocyte damage is an early event in the development of DN. Currently, there is no …

[HTML][HTML] Mesenchymal Stem Cell Therapy: Therapeutic Opportunities and Challenges for Diabetic Kidney Disease

J Cheng, C Zhang - International Journal of Molecular Sciences, 2024 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD),
which severely affects the quality of patients' lives. However, the current therapeutic …

[HTML][HTML] Podocyte Death in Diabetic Kidney Disease: Potential Molecular Mechanisms and Therapeutic Targets

S Zhong, N Wang, C Zhang - International Journal of Molecular Sciences, 2024 - mdpi.com
Cell deaths maintain the normal function of tissues and organs. In pathological conditions,
the abnormal activation or disruption of cell death often leads to pathophysiological effects …