Materials for implantable surface electrode arrays: current status and future directions

CM Tringides, DJ Mooney - Advanced Materials, 2022 - Wiley Online Library
Surface electrode arrays are mainly fabricated from rigid or elastic materials, and precisely
manipulated ductile metal films, which offer limited stretchability. However, the living tissues …

Paracrine effect of regulatory T cells promotes cardiomyocyte proliferation during pregnancy and after myocardial infarction

S Zacchigna, V Martinelli, S Moimas, A Colliva… - Nature …, 2018 - nature.com
Cardiomyocyte proliferation stops at birth when the heart is no longer exposed to maternal
blood and, likewise, to regulatory T cells (Tregs) that are expanded to promote maternal …

Remodelling of adult cardiac tissue subjected to physiological and pathological mechanical load in vitro

FG Pitoulis, R Nunez-Toldra, K Xiao… - Cardiovascular …, 2022 - academic.oup.com
Aims Cardiac remodelling is the process by which the heart adapts to its environment.
Mechanical load is a major driver of remodelling. Cardiac tissue culture has been frequently …

Increased myocardial stiffness activates cardiac microvascular endothelial cell via VEGF paracrine signaling in cardiac hypertrophy

J Shen, Y Xie, Z Liu, S Zhang, Y Wang, L Jia… - Journal of Molecular and …, 2018 - Elsevier
When the heart is subjected to an increased workload, mechanical stretch together with
neurohumoral stimuli activate the “fetal gene program” and induce cardiac hypertrophy to …

Biomechanical properties and mechanobiology of cardiac ECM

M Nguyen-Truong, Z Wang - Cardiac Extracellular Matrix: Fundamental …, 2018 - Springer
The heart is comprised of cardiac cells and extracellular matrix (ECM) which function
together to pump blood throughout the body, provide organs with nutrients and oxygen, and …

Pregnancy differentially regulates the collagens types I and III in left ventricle from rat heart

S Limon-Miranda, DG Salazar-Enriquez… - BioMed Research …, 2014 - Wiley Online Library
The pathologic cardiac remodeling has been widely documented; however, the
physiological cardiac remodeling induced by pregnancy and its reversion in postpartum are …

Ischemia-reperfusion injury and pregnancy initiate time-dependent and robust signs of up-regulation of cardiac progenitor cells

R Genead, H Fischer, A Hussain, M Jaksch… - PloS one, 2012 - journals.plos.org
To explore how cardiac regeneration and cell turnover adapts to disease, different forms of
stress were studied for their effects on the cardiac progenitor cell markers c-Kit and Isl1, the …

Pregnancy protects against antiangiogenic and fibrogenic effects of angiotensin II in rat hearts

MB Aljabri, NT Songstad, T Lund, MC Serrano… - Acta …, 2011 - Wiley Online Library
Aim: To investigate the difference between physiological and pathological cardiac
remodelling induced, respectively, by pregnancy and angiotensin (Ang) II, and to test the …

Effect of transverse aortic constriction on cardiac structure, function and gene expression in pregnant rats

NT Songstad, D Johansen, OJ How, PI Kaaresen… - PLoS …, 2014 - journals.plos.org
Background There is an increased risk of heart failure and pulmonary edema in pregnancies
complicated by hypertensive disorders. However, in a previous study we found that …

Matrix metalloproteinases system and types of fibrosis in rat heart during late pregnancy and postpartum

A Virgen-Ortiz, S Limón-Miranda, DG Salazar-Enríquez… - Medicina, 2019 - mdpi.com
Background and objectives: Cardiac remodeling in pregnancy and postpartum is poorly
understood. The aim of this study was to evaluate changes in cardiac fibrosis (pericardial …