Delivery of siRNAs Against Selective Ion Channels and Transporter Genes Using Hyaluronic Acid-coupled Carbonate Apatite Nanoparticles Synergistically Inhibits …

MB Uddin, MMB Holl, EH Chowdhury - International Journal of …, 2024 - Taylor & Francis
Introduction Dysregulated calcium homeostasis and consequentially aberrant Ca2+
signalling could enhance survival, proliferation and metastasis in various cancers. Despite …

NRF2 signaling pathway: A comprehensive prognostic and gene expression profile analysis in breast cancer

N Soghli, H Yousefi, T Naderi, A Fallah… - … -Research and Practice, 2023 - Elsevier
Breast cancer is the most frequently diagnosed malignant tumor in women and a major
public health concern. NRF2 axis is a cellular protector signaling pathway protecting both …

Carbonate apatite: effect of serum and impact on the cellular proteome

RA Islam, N Ibnat, MA Ashaie, SAZ Abidin… - Journal of Nanoparticle …, 2023 - Springer
Carbonate apatite (CA) is a synthetic derivative of hydroxyapatite, which we have been
exploring as a drug delivery nanocarrier in the context of cancer in vitro and in vivo. This …

Retarding breast tumor growth with nanoparticle-facilitated intravenous delivery of BRCA1 and BRCA2 tumor suppressor genes

N Ibnat, EH Chowdhury - Scientific Reports, 2023 - nature.com
Gene augmentation therapy entails replacement of the abnormal tumor suppressor genes in
cancer cells. In this study, we performed gene augmentation for BRCA1/2 tumor suppressors …