SNP Selection in Genome‐Wide Association Studies via Penalized Support Vector Machine with MAX Test

J Kim, I Sohn, D Kim, SH Jung - … and mathematical methods in …, 2013 - Wiley Online Library
One of main objectives of a genome‐wide association study (GWAS) is to develop a
prediction model for a binary clinical outcome using single‐nucleotide polymorphisms …

[HTML][HTML] Predictive and prognostic molecular markers for cholangiocarcinoma in Han Chinese population

L Meng, Z Tian, Y Wang, Y Liu, J Liu - International journal of …, 2015 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is the most common malignant heterogeneous polygenetic
carcinoma with a high incidence in Asia. Most patients would die within 1 year after …

Semivarying coefficient least-squares support vector regression for analyzing high-dimensional gene-environmental data

J Shim, C Hwang, S Jeong, I Sohn - Journal of Applied Statistics, 2018 - Taylor & Francis
In the context of genetics and genomic medicine, gene-environment (G× E) interactions
have a great impact on the risk of human diseases. Some existing methods for identifying G× …

Study of Ordinary Time to Event (OTE) residual in CPH model and its application in the genomic-wide time-to-event data analysis

R Mishra - 2024 - skemman.is
This study critically explored the Vieland et al.(2020) article, which introduced the Ordinary
Time to Event (OTE) residual. The primary objective of this study was to validate the claims …

[图书][B] Design, evaluation and application of methodology and software for time-to-event outcomes in pharmacogenetic genome-wide association studies

H Syed - 2018 - search.proquest.com
Design, Evaluation and Application of Methodology and Software for Time-to-event
Outcomes in Pharmacogenetic Genome-wide Association Studies Abstract Introduction and …

Estimation and variable selection in censored regression model with smoothly clipped absolute deviation penalty

J Shim, J Bae, K Seok - 한국데이터정보과학회지, 2016 - dbpia.co.kr
Smoothly clipped absolute deviation (SCAD) penalty is known to satisfy the desir-able
properties for penalty functions like as unbiasedness, sparsity and continuity. In this paper …

[图书][B] Functional genomic and proteomic analysis of highly drug resistant Chronic Myeloid Leukemia

DM Oaxaca - 2014 - search.proquest.com
Abstract Chronic Myeloid Leukemia (CML) has served as a model for how cancer can be
selectively targeted with advanced forms of chemotherapies known as kinase inhibitors …