[HTML][HTML] Data mining of Saccharomyces cerevisiae mutants engineered for increased tolerance towards inhibitors in lignocellulosic hydrolysates

E Cámara, L Olsson, J Zrimec, A Zelezniak… - Biotechnology …, 2022 - Elsevier
The use of renewable plant biomass, lignocellulose, to produce biofuels and biochemicals
using microbial cell factories plays a fundamental role in the future bioeconomy. The …

Acetic acid stress in budding yeast: From molecular mechanisms to applications

N Guaragnella, M Bettiga - Yeast, 2021 - Wiley Online Library
Acetic acid stress represents a frequent challenge to counteract for yeast cells under several
environmental conditions and industrial bioprocesses. The molecular mechanisms …

High-resolution lineage tracking reveals travelling wave of adaptation in laboratory yeast

AN Nguyen Ba, I Cvijović, JI Rojas Echenique… - Nature, 2019 - nature.com
In rapidly adapting asexual populations, including many microbial pathogens and viruses,
numerous mutant lineages often compete for dominance within the population,,,–. These …

Adaptive Response and Tolerance to Acetic Acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii: A Physiological Genomics Perspective

M Palma, JF Guerreiro, I Sá-Correia - Frontiers in Microbiology, 2018 - frontiersin.org
Acetic acid is an important microbial growth inhibitor in the food industry; it is used as a
preservative in foods and beverages and is produced during normal yeast metabolism in …

A new laboratory evolution approach to select for constitutive acetic acid tolerance in Saccharomyces cerevisiae and identification of causal mutations

D González-Ramos, AR Gorter de Vries… - Biotechnology for …, 2016 - Springer
Background Acetic acid, released during hydrolysis of lignocellulosic feedstocks for second
generation bioethanol production, inhibits yeast growth and alcoholic fermentation. Yeast …

Enhanced acetic acid stress tolerance and ethanol production in Saccharomyces cerevisiae by modulating expression of the de novo purine biosynthesis genes

MM Zhang, L Xiong, YJ Tang, MA Mehmood… - Biotechnology for …, 2019 - Springer
Background Yeast strains that are tolerant to multiple environmental stresses are highly
desired for various industrial applications. Despite great efforts in identifying key genes …

RNA-Seq-based transcriptomic and metabolomic analysis reveal stress responses and programmed cell death induced by acetic acid in Saccharomyces cerevisiae

Y Dong, J Hu, L Fan, Q Chen - Scientific reports, 2017 - nature.com
As a typical harmful inhibitor in cellulosic hydrolyzates, acetic acid not only hinders
bioethanol production, but also induces cell death in Saccharomyces cerevisiae. Herein, we …

Regulation of cell death induced by acetic acid in yeasts

SR Chaves, A Rego, VM Martins… - Frontiers in Cell and …, 2021 - frontiersin.org
Acetic acid has long been considered a molecule of great interest in the yeast research field.
It is mostly recognized as a by-product of alcoholic fermentation or as a product of the …

Xylitol: Production strategies with emphasis on biotechnological approach, scale up, and market trends

S Mathur, D Kumar, V Kumar, A Dantas… - Sustainable Chemistry …, 2023 - Elsevier
Xylitol, a sugar alcohol that is mostly derived from natural sources such as birch wood, corn
cobs, and various plant materials like berries, oats, and mushrooms shows promising …

How adaptive laboratory evolution can boost yeast tolerance to lignocellulosic hydrolyses

YA Menegon, J Gross, AP Jacobus - Current Genetics, 2022 - Springer
The yeast Saccharomyces cerevisiae is an excellent candidate for establishing cell factories
to convert lignocellulosic biomass into chemicals and fuels. To enable this technology, yeast …