A role for the host DNA damage response in hepatitis B virus cccDNA formation—and beyond?

S Schreiner, M Nassal - Viruses, 2017 - mdpi.com
Chronic hepatitis B virus (HBV) infection puts more than 250 million people at a greatly
increased risk to develop end-stage liver disease. Like all hepadnaviruses, HBV replicates …

Exploiting the human peptidome for novel antimicrobial and anticancer agents

M Bosso, L Ständker, F Kirchhoff, J Münch - Bioorganic & Medicinal …, 2018 - Elsevier
Infectious diseases and cancers are leading causes of death and pose major challenges to
public health. The human peptidome encompasses millions of compounds that display an …

Antiviral Mechanisms of Anisomycin Produced by Streptomyces albulus SN40 on Potato Virus Y

J Shu, K Cao, C Fei, H Dai, Y Li, Y Cao… - Journal of Agricultural …, 2024 - ACS Publications
Microbial secondary metabolites produced by Streptomyces have diverse application
prospects in the control of plant diseases. Herein, the fermentation filtrate of Streptomyces …

Reverse genetic approaches for the generation of recombinant Zika virus

G Ávila-Pérez, A Nogales, V Martín, F Almazán… - Viruses, 2018 - mdpi.com
Zika virus (ZIKV) is an emergent mosquito-borne member of the Flaviviridae family that was
responsible for a recent epidemic in the Americas. ZIKV has been associated with severe …

Reporter flaviviruses as tools to demonstrate homologous and heterologous superinfection exclusion

FJ Torres, R Parry, LE Hugo, A Slonchak, ND Newton… - Viruses, 2022 - mdpi.com
Binjari virus (BinJV) is a lineage II or dual-host affiliated insect-specific flavivirus previously
demonstrated as replication-deficient in vertebrate cells. Previous studies have shown that …

Infectious recombinant Senecavirus A expressing novel reporter proteins

M Wang, C Mou, M Chen, Z Chen - Applied Microbiology and …, 2021 - Springer
Senecavirus A (SVA) is an emerging picornavirus that has been associated with vesicular
disease and neonatal mortality in swine. The construction of SVA virus carrying foreign …

Development and characterization of recombinant tick-borne encephalitis virus expressing mCherry reporter protein: a new tool for high-throughput screening of …

J Haviernik, L Eyer, K Yoshii, S Kobayashi, J Cerny… - Antiviral Research, 2021 - Elsevier
The flavivirus, tick-borne encephalitis virus (TBEV) is transmitted by Ixodes spp. ticks and
may cause severe and potentially lethal neurological tick-borne encephalitis (TBE) in …

Development, characterization, and application of two reporter-expressing recombinant Zika viruses

SI Yun, BH Song, ME Woolley, JC Frank, JG Julander… - Viruses, 2020 - mdpi.com
Zika virus (ZIKV), a mosquito-borne transplacentally transmissible flavivirus, is an enveloped
virus with an~ 10.8 kb plus-strand RNA genome that can cause neurological disease. To …

Novel approach for insertion of heterologous sequences into full-length ZIKV genome results in superior level of gene expression and insert stability

E Volkova, KA Tsetsarkin, E Sippert, F Assis, G Liu… - Viruses, 2020 - mdpi.com
Zika virus (ZIKV) emerged in the Americas in 2015, presenting unique challenges to public
health. Unlike other arboviruses of the Flaviviridae family, it is transmissible by sexual …

In vivo Imaging-Driven approaches to study virus dissemination and pathogenesis

PD Uchil, KA Haugh, R Pi, W Mothes - Annual review of virology, 2019 - annualreviews.org
Viruses are causative agents for many diseases and infect all living organisms on the planet.
Development of effective therapies has relied on our ability to isolate and culture viruses in …