Pediatric mixed-phenotype acute leukemia: what's new?

S Batra, AJ Ross - Cancers, 2021 - mdpi.com
Simple Summary Pediatric mixed-phenotype leukemia is a rare form of blood cancer in
children. In this review, we cover both the evolution of treatment over the past several years …

The genome in a three-dimensional context: deciphering the contribution of noncoding mutations at enhancers to blood cancer

L Rovirosa, A Ramos-Morales, BM Javierre - Frontiers in immunology, 2020 - frontiersin.org
Associations between blood cancer and genetic predisposition, including both inherited
variants and acquired mutations and epimutations, have been well characterized. However …

Clinical features and next-generation sequencing landscape of essential thrombocythemia, prefibrotic primary myelofibrosis, and overt fibrotic primary myelofibrosis: a …

L Zhang, X Ye, S Luo, X Xu, S Wang, K Jin… - Journal of Cancer …, 2023 - Springer
Objective Since prefibrotic primary myelofibrosis (pre-PMF) was recognized as a separate
entity in the 2016 revised classification of MPN differed from essential thrombocythemia (ET) …

[HTML][HTML] Germline Single-Nucleotide Polymorphism GFI1-36N Causes Alterations in Mitochondrial Metabolism and Leads to Increased ROS-Mediated DNA Damage …

J Vorwerk, L Liu, TH Stadler, D Frank, HMM Ahmed… - Biomedicines, 2025 - mdpi.com
Background/Objectives: GFI1-36N represents a single-nucleotide polymorphism (SNP) of
the zinc finger protein Growth Factor Independence 1 (GFI1), in which the amino acid serine …

Das Strukturprotein SASH1 in der Tumorsuppression und der Pigmentierung–eine Näherung von der Maus zum Menschen

AR Sperlich - 2024 - mediatum.ub.tum.de
SASH1 gilt als Tumorsuppressor in diversen soliden Tumorentitäten und besitzt potenziell
Einfluss auf verschiedene (patho-) physiologische Vorgänge. Mit Hilfe zellbasierter …

[PDF][PDF] Interaktion zwischen mesenchymalen Zellen und AML-Blasten: die Rolle des Transkriptionsfaktors Gfi1

MN Fiori - 2024 - duepublico2.uni-due.de
Tumorsuppressoren eine Rolle (Toyota et al., 2001). Akute Leukämien werden meist durch
die Folgen einer gestörten Hämatopoese symptomatisch, denn leukämische Blasten …

Next-Generation Sequencing Mutational Landscape and Clinical Features of Chinese Adults with Myeloproliferative Neoplasms

S Luo, Z Wang, X Xu, L Zhang, S Wang, K Jin, J Huang - 2021 - researchsquare.com
Background: Myeloproliferative neoplasms (MPNs) include three classical subtypes:
polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF) …