Childhood nephrotic syndrome—current and future therapies

LA Greenbaum, R Benndorf, WE Smoyer - Nature reviews nephrology, 2012 - nature.com
The introduction of corticosteroids more than 50 years ago dramatically improved the
prognosis of children with nephrotic syndrome. Corticosteroids remain the standard initial …

Nutritional and other types of oedema, albumin, complex carbohydrates and the interstitium–a response to Malcolm Coulthard's hypothesis: Oedema in kwashiorkor is …

M Henry Golden - Paediatrics and international child health, 2015 - Taylor & Francis
The various types of oedema in man are considered in relation to Starling's hypothesis of
fluid movement from capillaries, with the main emphasis on nutritional oedema and the …

In vitro diagnostic examination and prognosis surveillance by hierarchical heterojunction-assisted metabolic analysis

F Shi, J Zhou, Y Wu, X Hu, Q Xie, C Deng… - Analytical …, 2022 - ACS Publications
High-throughput metabolic analysis based on laser desorption/ionization mass spectrometry
exhibits broad prospects in the field of large-scale precise medicine, for which the assisted …

Oxidative stress, inflammation and early cardiovascular damage in children with chronic renal failure

A Ece, F Gürkan, M Kervancıoğlu, H Kocamaz… - Pediatric …, 2006 - Springer
The relationship between inflammation, oxidant stress and cardiovascular damage in
children with chronic renal failure (CRF) has not previously been investigated. The aim of …

Changes of inflammatory mediators and oxidative stress indicators in children with Henoch-Schönlein purpura and clinical effects of hemoperfusion in the treatment of …

Y Zhu, Y Dong, L Wu, F Deng - BMC pediatrics, 2019 - Springer
Background To explore the changes of inflammatory and oxidative stress responses in
Henoch-Schönlein purpura (HSP) children, and further analyzed the therapeutic effects and …

Antioxidant enzyme activities, lipid peroxidation, and total antioxidant status in children with Henoch–Schönlein purpura

A Ece, S Kelekçi, H Kocamaz, A Hekimoğlu, H Balık… - Clinical …, 2008 - Springer
The aim of this study was to assess the role of oxidative stress in the pathogenesis of
Henoch–Schönlein purpura (HSP) vasculitis. The activities of catalase (CAT), arylesterase …

Antioxidant status of children with idiopathic nephrotic syndrome

OP Mishra, AK Gupta, R Prasad, Z Ali… - Pediatric …, 2011 - Springer
The production of free radicals can cause renal injury and play an important role in the
pathogenesis of idiopathic nephrotic syndrome. Markers of reactive oxygen species (ROS) …

Oxidative modification of low-density lipoprotein in relation to dyslipidemia and oxidant status in children with steroid sensitive nephrotic syndrome

NT El-Melegy, NA Mohamed, MM Sayed - Pediatric research, 2008 - nature.com
It has been proposed that nephrotic syndrome is a consequence of an imbalance between
oxidant/antioxidant statuses. The present study aimed to assess oxidant and antioxidant …

Oxidant stress in primary nephrotic syndrome: does it modulate the response to corticosteroids?

A Bakr, S Abul Hassan, M Shoker, M Zaki… - Pediatric Nephrology, 2009 - Springer
In order to assess the oxidative stress in newly diagnosed children with primary nephrotic
syndrome (PNS), we serially measured serum total antioxidant capacity (TAC) and …

Serum paraoxonase activity and oxidative stress in patients with adult nephrotic syndrome

YU Soyoral, M Aslan, H Emre, H Begenik, FM Erdur… - Atherosclerosis, 2011 - Elsevier
OBJECTIVE: It has been shown that low paraoxonase-1 (PON1) activity is associated with a
risk of an early development of atherosclerosis. In the present study, we investigated serum …