MicroRNA targeting

H Ghanbarian, MT Yıldız, Y Tutar - miRNomics: MicroRNA Biology and …, 2022 - Springer
MicroRNAs (miRNAs) are small noncoding elements that play essential roles in the
posttranscriptional regulation of biochemical processes. miRNAs recognize and target …

Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: past, present, and future

B Alural, S Genc, SJ Haggarty - Progress in Neuro-Psychopharmacology …, 2017 - Elsevier
Neuropsychiatric disorders are common health problems affecting approximately 1% of the
population. Twin, adoption, and family studies have displayed a strong genetic component …

MicroRNA-mediated regulatory circuits: outlook and perspectives

A Re, M Caselle, F Bussolino - Physical biology, 2017 - iopscience.iop.org
MicroRNAs have been found to be necessary for regulating genes implicated in almost all
signaling pathways, and consequently their dysfunction influences many diseases, including …

Review of databases for experimentally validated human microRNA–mRNA interactions

D Kariuki, K Asam, BE Aouizerat, KA Lewis… - Database, 2023 - academic.oup.com
MicroRNAs (miRs) may contribute to disease etiology by influencing gene expression.
Numerous databases are available for miR target prediction and validation, but their …

[HTML][HTML] miRTex: a text mining system for miRNA-gene relation extraction

G Li, KE Ross, CN Arighi, Y Peng, CH Wu… - PLoS computational …, 2015 - journals.plos.org
MicroRNAs (miRNAs) regulate a wide range of cellular and developmental processes
through gene expression suppression or mRNA degradation. Experimentally validated …

Human miR-3145 inhibits influenza A viruses replication by targeting and silencing viral PB1 gene

K Khongnomnan, J Makkoch… - Experimental …, 2015 - journals.sagepub.com
MicroRNAs (miRNAs) play an important role in the regulation of gene expression and are
involved in many cellular processes including inhibition of viral replication in infected cells …

[HTML][HTML] miRNA–mRNA Integrated Analysis Reveals Roles for miRNAs in a Typical Halophyte, Reaumuria soongorica, during Seed Germination under Salt Stress

H Zhang, X Liu, X Yang, H Wu, J Zhu, H Zhang - Plants, 2020 - mdpi.com
MicroRNAs (miRNAs) are endogenous small RNAs that play a crucial role in plant growth,
development, and environmental stress responses. Reaumuria soongorica is a typical …

Recent development of bioinformatics tools for microRNA target prediction

MS Khatun, MA Alam, W Shoombuatong… - Current medicinal …, 2022 - ingentaconnect.com
MicroRNAs (miRNAs) are central players that regulate the post-transcriptional processes of
gene expression. Binding of miRNAs to target mRNAs can repress their translation by …

[HTML][HTML] PTRE-seq reveals mechanism and interactions of RNA binding proteins and miRNAs

KA Cottrell, HG Chaudhari, BA Cohen… - Nature …, 2018 - nature.com
RNA binding proteins (RBP) and microRNAs (miRNAs) often bind sequences in 3′
untranslated regions (UTRs) of mRNAs, and regulate stability and translation efficiency. With …

Delivery and targeting of miRNAs for treating liver fibrosis

V Kumar, RI Mahato - Pharmaceutical research, 2015 - Springer
Liver fibrosis is a pathological condition originating from liver damage that leads to excess
accumulation of extracellular matrix (ECM) proteins in the liver. Viral infection, chronic injury …