Crosstalk of T cells within the ovarian cancer microenvironment

BS Chap, N Rayroux, AJ Grimm, E Ghisoni, DD Laniti - Trends in Cancer, 2024 - cell.com
Ovarian cancer (OC) represents ecosystems of highly diverse tumor microenvironments
(TMEs). The presence of tumor-infiltrating lymphocytes (TILs) is linked to enhanced immune …

[HTML][HTML] Comparative analysis of multiplexed in situ gene expression profiling technologies

A Hartman, R Satija - eLife, 2024 - elifesciences.org
The burgeoning interest in in situ multiplexed gene expression profiling technologies has
opened new avenues for understanding cellular behavior and interactions. In this study, we …

Next‐generation spatial transcriptomics: unleashing the power to gear up translational oncology

N Wang, W Hong, Y Wu, ZS Chen, M Bai, W Wang… - MedComm, 2024 - Wiley Online Library
The growing advances in spatial transcriptomics (ST) stand as the new frontier bringing
unprecedented influences in the realm of translational oncology. This has triggered systemic …

The unveiled mosaic of intra-tumor heterogeneity in ovarian cancer through spatial transcriptomic technologies: A systematic review

L Masatti, M Marchetti, S Pirrotta, G Spagnol… - Translational …, 2024 - Elsevier
Epithelial ovarian cancer is a significant global health issue among women. Diagnosis and
treatment pose challenges due to difficulties in predicting patient responses to therapy …