The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
R Bany Bakar, F Reimann, FM Gribble - … reviews Gastroenterology & …, 2023 - nature.com
Gut hormones orchestrate pivotal physiological processes in multiple metabolically active
tissues, including the pancreas, liver, adipose tissue, gut and central nervous system …
tissues, including the pancreas, liver, adipose tissue, gut and central nervous system …
Biology of incretins: GLP-1 and GIP
LL Baggio, DJ Drucker - Gastroenterology, 2007 - Elsevier
This review focuses on the mechanisms regulating the synthesis, secretion, biological
actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic …
actions, and therapeutic relevance of the incretin peptides glucose-dependent insulinotropic …
The incretin hormone GLP‐1 and mechanisms underlying its secretion: 肠促胰岛素激素GLP‐1 及其潜在的分泌机制
L Tian, T Jin - Journal of diabetes, 2016 - Wiley Online Library
摘要胰高血糖素样肽‐1 (Glucagon‐like peptide‐1, GLP‐1) 是一种细胞类型特异性的胰高血糖
素原翻译后产物. 它是由胰高血糖素原基因所编码的, 在激素, 神经元以及营养的刺激下主要由肠 …
素原翻译后产物. 它是由胰高血糖素原基因所编码的, 在激素, 神经元以及营养的刺激下主要由肠 …
Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV
AM Lambeir, C Durinx, S Scharpé… - Critical reviews in …, 2003 - Taylor & Francis
Dipeptidyl-peptidase IV/CD26 (DPP IV) is a cell-surface protease belonging to the
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …
prolyloligopeptidase family. It selectively removes the N-terminal dipeptide from peptides …
The glucagon-like peptides
TJ Kieffer, J Francis Habener - Endocrine reviews, 1999 - academic.oup.com
Glucagon-Like Peptides | Endocrine Reviews | Oxford Academic Skip to Main Content
Advertisement Oxford Academic Journals Books Search Menu Information Account Menu …
Advertisement Oxford Academic Journals Books Search Menu Information Account Menu …
Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion
AS Rocca, PL Brubaker - Endocrinology, 1999 - academic.oup.com
Plasma levels of glucagon-like peptide-1 (GLP-1) rise rapidly after nutrient ingestion,
suggesting the existence of a proximal gut signal regulating GLP-1 release from the L cells …
suggesting the existence of a proximal gut signal regulating GLP-1 release from the L cells …
Glucagon-like peptides
DJ Drucker - Diabetes, 1998 - Am Diabetes Assoc
Proglucagon contains the sequence of two glucagonlike peptides, GLP-1 and GLP-2,
secreted from enteroendocrine cells of the small and large intestine. GLP-1 lowers blood …
secreted from enteroendocrine cells of the small and large intestine. GLP-1 lowers blood …
Biological actions and therapeutic potential of the glucagon-like peptides
DJ Drucker - Gastroenterology, 2002 - Elsevier
The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides
cosecreted from gut endocrine cells in response to nutrient ingestion. GLP-1 acts as an …
cosecreted from gut endocrine cells in response to nutrient ingestion. GLP-1 acts as an …
Incretin hormones and type 2 diabetes—mechanistic insights and therapeutic approaches
Simple Summary When we ingest a meal, our intestine secretes hormones that are released
into the bloodstream. Amongst these hormones are the incretins hormones which stimulate …
into the bloodstream. Amongst these hormones are the incretins hormones which stimulate …
Minireview: the glucagon-like peptides
DJ Drucker - Endocrinology, 2001 - academic.oup.com
The glucagon-like peptides GLP-1 and GLP-2 are produced in enteroendocrine L cells of
the small and large intestine and secreted in a nutrient-dependent manner. GLP-1 regulates …
the small and large intestine and secreted in a nutrient-dependent manner. GLP-1 regulates …