Deciphering the endometrial immune landscape of RIF during the window of implantation from cellular senescence by integrated bioinformatics analysis and machine …
X Zhao, Y Zhao, Y Jiang, Q Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Recurrent implantation failure (RIF) is an extremely thorny issue in in-vitro fertilization (IVF)-
embryo transfer (ET). However, its intricate etiology and pathological mechanisms are still …
embryo transfer (ET). However, its intricate etiology and pathological mechanisms are still …
Detecting and dissecting signaling crosstalk via the multilayer network integration of signaling and regulatory interactions
The versatility of cellular response arises from the communication, or crosstalk, of signaling
pathways in a complex network of signaling and transcriptional regulatory interactions …
pathways in a complex network of signaling and transcriptional regulatory interactions …
XTalkDB: a database of signaling pathway crosstalk
SA Sam, J Teel, AN Tegge, A Bharadwaj… - Nucleic acids …, 2017 - academic.oup.com
Abstract Analysis of signaling pathways and their crosstalk is a cornerstone of systems
biology. Thousands of papers have been published on these topics. Surprisingly, there is no …
biology. Thousands of papers have been published on these topics. Surprisingly, there is no …
Experimentally-driven mathematical model to understand the effects of matrix deprivation in breast cancer metastasis
S Maiti, A Rangarajan, V Kareenhalli - NPJ systems biology and …, 2024 - nature.com
Normal epithelial cells receive proper signals for growth and survival from attachment to the
underlying extracellular matrix (ECM). They perceive detachment from the ECM as a stress …
underlying extracellular matrix (ECM). They perceive detachment from the ECM as a stress …
Co‐Targeting Plk1 and DNMT3a in Advanced Prostate Cancer
Because there is no effective treatment for late‐stage prostate cancer (PCa) at this moment,
identifying novel targets for therapy of advanced PCa is urgently needed. A new network …
identifying novel targets for therapy of advanced PCa is urgently needed. A new network …
GraphSpace: stimulating interdisciplinary collaborations in network biology
Networks have become ubiquitous in systems biology. Visualization is a crucial component
in their analysis. However, collaborations within research teams in network biology are …
in their analysis. However, collaborations within research teams in network biology are …
PINTnet: construction of condition-specific pathway interaction network by computing shortest paths on weighted PPI
Background Identifying perturbed pathways in a given condition is crucial in understanding
biological phenomena. In addition to identifying perturbed pathways individually, pathway …
biological phenomena. In addition to identifying perturbed pathways individually, pathway …
[图书][B] Computational methods for processing and analysis of biological pathways
This work offers a guided walkthrough of one of the most promising research areas in
modern life sciences, enabling a deeper understanding of involved concepts and …
modern life sciences, enabling a deeper understanding of involved concepts and …
Augmenting signaling pathway reconstructions
Signaling pathways drive cellular response, and understanding such pathways is
fundamental to molecular systems biology. A mounting volume of experimental protein …
fundamental to molecular systems biology. A mounting volume of experimental protein …
Detecting pathway relationship in the context of human protein-protein interaction network and its application to Parkinson's disease
In human physiological conditions like complex diseases, a large number of genes/proteins,
as well as their interactions, are involved. Thus, detecting the biochemical pathways …
as well as their interactions, are involved. Thus, detecting the biochemical pathways …