NF-κB, inflammation, immunity and cancer: coming of age

K Taniguchi, M Karin - Nature Reviews Immunology, 2018 - nature.com
Fourteen years have passed since nuclear factor-κB (NF-κB) was first shown to serve as a
molecular lynchpin that links persistent infections and chronic inflammation to increased …

Interplay between inflammation and cancer

I Piotrowski, K Kulcenty… - Reports of Practical …, 2020 - journals.viamedica.pl
Tumor-promoting inflammation is one of the hallmarks of cancer. It has been shown that
cancer development is strongly influenced by both chronic and acute inflammation process …

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer …

JS Vaidya, M Bulsara, M Baum, F Wenz, S Massarut… - bmj, 2020 - bmj.com
Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a
single dose during lumpectomy, can effectively replace postoperative whole breast external …

[HTML][HTML] Inflammation-triggered cancer immunotherapy by programmed delivery of CpG and anti-PD1 antibody

C Wang, W Sun, G Wright, A Wang… - … materials (Deerfield Beach …, 2016 - ncbi.nlm.nih.gov
Inflammation-triggered combination delivery of anti-PD-1 antibody (aPD1) and CpG
oligodeoxynucleotides (CpG ODNs) has been demonstrated to prevent cancer relapse …

Role of STAT3 in the initiation, progression, proliferation and metastasis of breast cancer and strategies to deliver JAK and STAT3 inhibitors

YH Dinakar, H Kumar, SL Mudavath, R Jain, R Ajmeer… - Life Sciences, 2022 - Elsevier
Introduction Breast cancer (BC) accounts for the majority of cancers among the female
population. Anomalous activation of various signaling pathways has become an issue of …

Effect of delayed targeted intraoperative radiotherapy vs whole-breast radiotherapy on local recurrence and survival: long-term results from the TARGIT-A randomized …

JS Vaidya, M Bulsara, C Saunders, H Flyger… - JAMA …, 2020 - jamanetwork.com
Importance Conventional adjuvant radiotherapy for breast cancer given daily for several
weeks is onerous and expensive. Some patients may be obliged to choose a mastectomy …

The largest multicentre data collection on prepectoral breast reconstruction: the iBAG study

J Masià, iBAG Working Group… - Journal of surgical …, 2020 - Wiley Online Library
Abstract Background and Objectives In the last years, prepectoral breast reconstruction has
increased its popularity, becoming a standard reconstructive technique by preserving …

The tumor microenvironment in the postsurgical liver: Mechanisms and potential targets of postoperative recurrence in human hepatocellular carcinoma

J Wu, YT Chan, Y Lu, N Wang… - Medicinal Research …, 2023 - Wiley Online Library
Surgery remains to be the mainstay of treatment for hepatocellular carcinoma (HCC).
Nonetheless, its therapeutic efficacy is significantly impaired by postoperative recurrence …

Impact of time from completion of neoadjuvant chemotherapy to surgery on survival outcomes in breast cancer patients

RA Sanford, X Lei, CH Barcenas, EA Mittendorf… - Annals of surgical …, 2016 - Springer
Background No studies have examined the impact of the interval from conclusion of
neoadjuvant chemotherapy to surgery in breast cancer patients. This study was undertaken …

The application of nanoparticles in theranostic systems targeting breast cancer stem cells: current progress and future challenges

X Lin, Y Wang, K Fang, Z Guo, N Lin, L Li - Stem Cell Research & Therapy, 2023 - Springer
Breast cancer (BC) is one of the diseases with the highest female mortality rates in the world
and is closely related to breast cancer stem cells (BCSCs). Conventional breast cancer …