Insulin dysregulation is the hallmark of equine metabolic syndrome and has received
attention because of its direct association with laminitis. In the absence of an adequate …

Although much has been written about laminitis in the context of its association with
inflammatory processes, such as dietary carbohydrate overload and endotoxemia, 1–5 …

Billions of bacteria inhabit the gastrointestinal tract. Immune-microbial cross talk is
responsible for immunological homeostasis, and symbiotic microbial species induce …

Obesity and endocrine disorders have become prevalent issues in the field of both human
and veterinary medicine. Equine metabolic syndrome is a complex disorder involving …

Background: Insulin resistance has been associated with risk of laminitis in horses. Genes
coding for proinflammatory cytokines and chemokines are expressed more in visceral …

Advanced age is associated with a low-grade, systemic inflammatory response
characterized by increased inflammatory cytokine production both in vitro and in vivo …

Background Obesity and hyperinsulinemia increase the risk of laminitis in horses and
ponies. In mares, obesity also has been associated with increased circulating …

Obesity and metabolic disorders are associated with systemic low-grade chronic
inflammation, both in humans and animals. The aim of the study is to assess the effects of …

There is growing recognition that obesity is common and represents a significant detriment
to the health of companion animals in a manner similar to that by which it is affecting the …

Obesity has become a serious health problem with frequent occurrence both in human and
animal populations. It is estimated that it may affect over 85% of the human population and …