Psychiatric comorbidities in people with epilepsy

M Mula, AM Kanner, N Jetté… - Neurology: Clinical …, 2021 - AAN Enterprises
Purpose of Review To review the latest evidence concerning the epidemiology, clinical
implications, and management of psychiatric disorders in epilepsy. Recent Findings People …

Individualised prediction of drug resistance and seizure recurrence after medication withdrawal in people with juvenile myoclonic epilepsy: a systematic review and …

R Stevelink, D Al-Toma, FE Jansen, HJ Lamberink… - …, 2022 - thelancet.com
Background A third of people with juvenile myoclonic epilepsy (JME) are drug-resistant.
Three-quarters have a seizure relapse when attempting to withdraw anti-seizure medication …

ILAE definition of the idiopathic generalized epilepsy syndromes: position statement by the ILAE task force on nosology and definitions

E Hirsch, J French, IE Scheffer, A Bogacz, T Alsaadi… - …, 2022 - Wiley Online Library
Abstract In 2017, the International League Against Epilepsy (ILAE) Classification of
Epilepsies described the “genetic generalized epilepsies”(GGEs), which contained the …

A comprehensive review of emerging trends and innovative therapies in epilepsy management

S Ghosh, JK Sinha, S Ghosh, H Sharma, R Bhaskar… - Brain Sciences, 2023 - mdpi.com
Epilepsy is a complex neurological disorder affecting millions worldwide, with a substantial
number of patients facing drug-resistant epilepsy. This comprehensive review explores …

Sex-specific disease modifiers in juvenile myoclonic epilepsy

A Shakeshaft, N Panjwani, A Collingwood… - Scientific reports, 2022 - nature.com
Juvenile myoclonic epilepsy (JME) is a common idiopathic generalised epilepsy with
variable seizure prognosis and sex differences in disease presentation. Here, we investigate …

Genetic generalized epilepsies in adults—challenging assumptions and dogmas

BJ Vorderwülbecke, B Wandschneider… - Nature Reviews …, 2022 - nature.com
Genetic generalized epilepsy (GGE) syndromes start during childhood or adolescence, and
four commonly persist into adulthood, making up 15–20% of all cases of epilepsy in adults …

Neuropsychiatric and cognitive comorbidities in epilepsy

M Mula, H Coleman, SJ Wilson - CONTINUUM: Lifelong Learning …, 2022 - journals.lww.com
Neuropsychiatric and Cognitive Comorbidities in Epilepsy : CONTINUUM: Lifelong
Learning in Neurology Account Register Activate Subscription Help Subscribe American …

Epidemiology and outcome of idiopathic generalized epilepsy in adults

J Gesche, J Christensen, H Hjalgrim… - European Journal of …, 2020 - Wiley Online Library
Background and purpose Drug‐resistant idiopathic generalized epilepsy (IGE) remains
challenging despite a favourable overall prognosis of IGE, and little is known about basic …

Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets

BE Lindquist, C Timbie, Y Voskobiynyk, JT Paz - Neurobiology of disease, 2023 - Elsevier
Generalized epilepsy affects 24 million people globally; at least 25% of cases remain
medically refractory. The thalamus, with widespread connections throughout the brain, plays …

Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy

BK Kamitaki, M Janmohamed, P Kandula, C Elder… - …, 2022 - Wiley Online Library
Objective We sought to determine which combination of clinical and
electroencephalography (EEG) characteristics differentiate between an antiseizure …