New Frontiers in Asthma Chest Imaging

AM Matheson, J Johnstone, PJ Niedbalski… - Journal of Allergy and …, 2024 - Elsevier
Modern pulmonary imaging can reveal underlying pathological and pathophysiological
changes in the lungs of people with asthma, with important clinical implications. A multitude …

A new approach to computed tomography measurement of airway remodelling in paediatric asthma

SB Fain, MJ McIntosh - ERJ open research, 2024 - Eur Respiratory Soc
Extract The Global Initiative for Asthma (GINA) defines severe asthma as a subset of difficult-
to-treat asthma that is refractory to oral or inhaled corticosteroid therapies despite …

Impaired diffusion at submaximal lung inflation in asthma and copd patients

S Verbanck, M Hughes - Respiratory Physiology & Neurobiology, 2024 - Elsevier
Abstract Introduction Dissolved-phase 129 Xe MRI metrics suggest that gas diffusion may be
more compromised at submaximal lung inflation compared to maximal inflation. We …

Pulmonary 129Xe Magnetic Resonance Gas-exchange Abnormalities in Moderate-Severe Asthma

G Parraga, S Tcherner, A Mozaffaripour, AM Matheson… - medRxiv, 2024 - medrxiv.org
BACKGROUND: Asthma is recognized as an inflammatory disease of the airways, but
inflammation may also affect the parenchyma and pulmonary vasculature. Hyperpolarized …

129Xe Magnetic Resonance Imaging Ventilation Phenotypes of Severe Asthma

A Thakar - 2024 - macsphere.mcmaster.ca
INTRODUCTION: Abnormal ventilation is the functional consequence of airway obstruction.
In patients with severe asthma, ventilation patterns visualized by magnetic resonance …