Oral commensal streptococci: gatekeepers of the oral cavity

JJ Baty, SN Stoner, JA Scoffield - Journal of Bacteriology, 2022 - Am Soc Microbiol
Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …

Streptococcus gordonii: Pathogenesis and Host Response to Its Cell Wall Components

OJ Park, Y Kwon, C Park, YJ So, TH Park, S Jeong… - Microorganisms, 2020 - mdpi.com
Streptococcus gordonii, a Gram-positive bacterium, is a commensal bacterium that is
commonly found in the skin, oral cavity, and intestine. It is also known as an opportunistic …

Oral Propolis Nanoemulsions Modulate Gut Microbiota to Balance Bone Remodeling for Enhanced Osteoporosis Therapy

Y Zheng, Z Zhang, Z Fu, A Fan, N Song, Q Wang… - ACS …, 2024 - ACS Publications
The discovery of the bone–gut axis linking bone metabolism to gut microbiota (GM)
dysbiosis has revolutionized our understanding of managing degenerative skeletal …

The impacts of oral and gut microbiota on alveolar bone loss in periodontitis

N Han, X Li, J Du, J Xu, L Guo… - Journal of Periodontal …, 2023 - Wiley Online Library
Periodontitis, a chronic infectious disease, primarily arises from infections and the invasion
of periodontal pathogens. This condition is typified by alveolar bone loss resulting from host …

Inflammatory macrophages exploited by oral streptococcus increase IL-1B release via NLRP6 inflammasome

S Metcalfe, M Panasiewicz… - Journal of Leukocyte …, 2023 - academic.oup.com
Chronic inflammatory periodontal disease develops in part from the infiltration of a large
number of classically activated inflammatory macrophages that release inflammatory …

The relationship between osteoporosis and intestinal microbes in the Henan Province of China

Q Qin, S Yan, Y Yang, J Chen, H Yan, T Li… - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoporosis (OP) is a chronic disease in the elderly, and China is entering an aging
demographic trend. In recent years, increasing evidence has demonstrated that probiotics …

Metformin reduces bone resorption in apical periodontitis through regulation of osteoblast and osteoclast differentiation

CY Hong, SK Lin, HW Wang, CT Shun, CN Yang… - Journal of …, 2023 - Elsevier
Introduction We have previously demonstrated that auxiliary metformin therapy promotes
healing of apical periodontitis. Here we aimed to investigate the effects of metformin on …

Effects of extracellular vesicles derived from oral bacteria on osteoclast differentiation and activation

HY Kim, MK Song, Y Lim, JS Jang, SJ An, HH Kim… - Scientific Reports, 2022 - nature.com
Dysbiosis of the oral microbiota plays an important role in the progression of periodontitis,
which is characterized by chronic inflammation and alveolar bone loss, and associated with …

A review on saliva-based health diagnostics: biomarker selection and future directions

S Kumari, M Samara, R Ampadi Ramachandran… - Biomedical Materials & …, 2024 - Springer
The human body has a unique way of saying when something is wrong with it. The
molecules in the body fluids can be helpful in the early detection of diseases by enabling …

Induction of apoptotic cell death by oral streptococci in human periodontal ligament cells

OJ Park, AR Kim, YJ So, J Im, HJ Ji, KB Ahn… - Frontiers in …, 2021 - frontiersin.org
Initiation and progression of oral infectious diseases are associated with streptococcal
species. Bacterial infection induces inflammatory responses together with reactive oxygen …