PharmVar GeneFocus: CYP2D6
C Nofziger, AJ Turner, K Sangkuhl… - Clinical …, 2020 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly
polymorphic human CYP2D6 gene locus. CYP2D6 genetic variation impacts the metabolism …
polymorphic human CYP2D6 gene locus. CYP2D6 genetic variation impacts the metabolism …
Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good
The field of pharmacogenomics (PGx) is gradually shifting from the reactive testing of single
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
genes toward the proactive testing of multiple genes to improve treatment outcomes, reduce …
Comprehensive genome analysis and variant detection at scale using DRAGEN
Research and medical genomics require comprehensive, scalable methods for the
discovery of novel disease targets, evolutionary drivers and genetic markers with clinical …
discovery of novel disease targets, evolutionary drivers and genetic markers with clinical …
PharmVar GeneFocus: CYP2C19
MR Botton, M Whirl‐Carrillo… - Clinical …, 2021 - Wiley Online Library
The Pharmacogene Variation Consortium (PharmVar) catalogues star (*) allele
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …
nomenclature for the polymorphic human CYP2C19 gene. CYP2C19 genetic variation …
[HTML][HTML] Recommendations for clinical CYP2D6 genotyping allele selection: a joint consensus recommendation of the Association for Molecular Pathology, College of …
VM Pratt, LH Cavallari, AL Del Tredici… - The Journal of Molecular …, 2021 - Elsevier
The goals of the Association for Molecular Pathology Clinical Practice Committee's
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Reference standards for next-generation sequencing
Next-generation sequencing (NGS) provides a broad investigation of the genome, and it is
being readily applied for the diagnosis of disease-associated genetic features. However, the …
being readily applied for the diagnosis of disease-associated genetic features. However, the …
Pharmacogenetics at scale: an analysis of the UK Biobank
Pharmacogenetics (PGx) studies the influence of genetic variation on drug response.
Clinically actionable associations inform guidelines created by the Clinical …
Clinically actionable associations inform guidelines created by the Clinical …
[HTML][HTML] Recommendations for clinical CYP2C19 genotyping allele selection: a report of the Association for Molecular Pathology
This document was developed by the Pharmacogenomics (PGx) Working Group of the
Association for Molecular Pathology Clinical Practice Committee, whose aim is to …
Association for Molecular Pathology Clinical Practice Committee, whose aim is to …
DPYD genotyping recommendations: a joint consensus recommendation of the association for molecular pathology, American college of medical genetics and …
VM Pratt, LH Cavallari, ML Fulmer, A Gaedigk… - The Journal of Molecular …, 2024 - Elsevier
The goals of the Association for Molecular Pathology (AMP) Clinical Practice Committee's
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Pharmacogenomics (PGx) Working Group are to define the key attributes of …
Genophenotypic factors and pharmacogenomics in adverse drug reactions
R Cacabelos, V Naidoo, L Corzo, N Cacabelos… - International journal of …, 2021 - mdpi.com
Adverse drug reactions (ADRs) rank as one of the top 10 leading causes of death and
illness in developed countries. ADRs show differential features depending upon genotype …
illness in developed countries. ADRs show differential features depending upon genotype …