Prions are unprecedented infectious pathogens that cause a group of invariably fatal
neurodegenerative diseases by an entirely novel mechanism. Prion diseases may present …

Exosomes are nanovesicles secreted into the extracellular environment upon internal
vesicle fusion with the plasma membrane. The molecular content of exosomes is a …

The development of technologies for the in vitro amplification of abnormal conformations of
prion protein (PrPSc) has generated the potential for sensitive detection of prions. Here we …

▪ Abstract Many neurodegenerative diseases, including Alzheimer's and Parkinson's and the
transmissible spongiform encephalopathies (prion diseases), are characterized at autopsy …

▪ Abstract Prion diseases are transmissible neurodegenerative conditions that include
Creutzfeldt-Jakob disease (CJD) in humans and bovine spongiform encephalopathy (BSE) …

Prions are lethal mammalian pathogens composed of aggregated conformational isomers of
a host-encoded glycoprotein and which appear to lack nucleic acids. Their unique biology …

Epidemiological and clinicopathological studies, allied with pathological prion protein
(PrPSc) analysis, strongly support the hypothesis that the human prion disease new variant …

Prions are notorious protein-only infectious agents that cause invariably fatal brain diseases
following silent incubation periods that can span a lifetime. These diseases can arise …

Rhetorical Figures in Science breaks new ground in the rhetorical study of scientific
argument as the first book to demonstrate how figures of speech other than metaphor have …

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