Melatonin potentials against viral infections including COVID-19: Current evidence and new findings

KB Juybari, MH Pourhanifeh, A Hosseinzadeh… - Virus research, 2020 - Elsevier
Viral infections are dangerous diseases for human health worldwide, which lead to
significant morbidity and mortality each year. Because of their importance and the lack of …

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

A Fernández, R Ordóñez, RJ Reiter… - Journal of pineal …, 2015 - Wiley Online Library
Endoplasmic reticulum (ER) is a dynamic organelle that participates in a number of cellular
functions by controlling lipid metabolism, calcium stores, and proteostasis. Under stressful …

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes

DX Tan, LC Manchester, X Liu… - Journal of pineal …, 2013 - Wiley Online Library
Mitochondria and chloroplasts are major sources of free radical generation in living
organisms. Because of this, these organelles require strong protection from free radicals and …

A review of the molecular aspects of melatonin's anti‐inflammatory actions: recent insights and new perspectives

JL Mauriz, PS Collado, C Veneroso… - Journal of pineal …, 2013 - Wiley Online Library
Melatonin is a highly evolutionary conserved endogenous molecule that is mainly produced
by the pineal gland, but also by other nonendocrine organs, of most mammals including …

Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a review

J Abrantes, W van Der Loo, J Le Pendu, PJ Esteves - Veterinary research, 2012 - Springer
Rabbit haemorrhagic disease virus (RHDV) is a calicivirus of the genus Lagovirus that
causes rabbit haemorrhagic disease (RHD) in adult European rabbits (Oryctolagus …

Melatonin and the theories of aging: a critical appraisal of melatonin's role in antiaging mechanisms

R Hardeland - Journal of pineal research, 2013 - Wiley Online Library
The classic theories of aging such as the free radical theory, including its mitochondria‐
related versions, have largely focused on a few specific processes of senescence …

The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives

R J. Reiter, DX Tan, S Rosales-Corral… - Mini reviews in …, 2013 - benthamdirect.com
Melatonin is an uncommonly widely distributed molecule. It is found throughout the plant
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …

[HTML][HTML] Hepatic TGFβr1 deficiency attenuates lipopolysaccharide/D-galactosamine–induced acute liver failure through inhibiting GSK3β–Nrf2–mediated hepatocyte …

S Huang, Y Wang, S Xie, Y Lai, C Mo, T Zeng… - Cellular and molecular …, 2022 - Elsevier
Background & Aims Acute liver failure (ALF) is a condition with high mortality and morbidity,
characterized by glutathione depletion, oxidative stress, and mitochondrial dysfunction …

SARS-CoV-2 and other coronaviruses negatively influence mitochondrial quality control: beneficial effects of melatonin

S Mehrzadi, MY Karimi, A Fatemi, RJ Reiter… - Pharmacology & …, 2021 - Elsevier
Coronaviruses (CoVs) are a group of single stranded RNA viruses, of which some of them
such as SARS-CoV, MERS-CoV, and SARS-CoV-2 are associated with deadly worldwide …

[HTML][HTML] Melatonin protects rats testes against bleomycin, etoposide, and cisplatin-induced toxicity via mitigating nitro-oxidative stress and apoptosis

M Moradi, N Goodarzi, A Faramarzi, H Cheraghi… - Biomedicine & …, 2021 - Elsevier
There is growing concern that some cytotoxic regimens for cancer adversely affect
spermatogenesis and male fertility. Increasing evidence demonstrated that melatonin has …