Hydrogels for 3D mammalian cell culture: a starting guide for laboratory practice

F Ruedinger, A Lavrentieva, C Blume… - Applied microbiology …, 2015 - Springer
Hydrogels have become one of the most popular platforms for three-dimensional (3D)
cultivation of mammalian cells. The enormous versatility of hydrogel materials makes it …

Cell form and function: interpreting and controlling the shape of adherent cells

A Prasad, E Alizadeh - Trends in biotechnology, 2019 - cell.com
Beautiful images of animal cells cultured on surfaces are ubiquitous in biological research,
but these shapes also carry valuable information about the cells and the organism that they …

Merging machine learning and bioelectronics for closed-loop control of biological systems and homeostasis

M Jafari, G Marquez, H Dechiraju, M Gomez… - Cell Reports Physical …, 2023 - cell.com
The regulation of most physiological processes relies on a state of equilibrium called
homeostasis, which is achieved through a biological control loop involving sensors and …

Investigating heterogeneities of live mesenchymal stromal cells using AI-based label-free imaging

S Imboden, X Liu, BS Lee, MC Payne, CJ Hsieh… - Scientific Reports, 2021 - nature.com
Mesenchymal stromal cells (MSCs) are multipotent cells that have great potential for
regenerative medicine, tissue repair, and immunotherapy. Unfortunately, the outcomes of …

SIRT3 enhances mesenchymal stem cell longevity and differentiation

RA Denu - Oxidative medicine and cellular longevity, 2017 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells that are currently being investigated in
a wide variety of clinical trials for their anti‐inflammatory and immunomodulatory properties …

Automated mesenchymal stem cell segmentation and machine learning-based phenotype classification using morphometric and textural analysis

SM Mota, RE Rogers, AW Haskell… - Journal of medical …, 2021 - spiedigitallibrary.org
Purpose: Mesenchymal stem cells (MSCs) have demonstrated clinically relevant therapeutic
effects for treatment of trauma and chronic diseases. The proliferative potential …

Diversity of dermal fibroblasts as major determinant of variability in cell reprogramming

AM Sacco, I Belviso, V Romano… - Journal of Cellular …, 2019 - Wiley Online Library
Induced pluripotent stem cells (iPSCs) are adult somatic cells genetically reprogrammed to
an embryonic stem cell‐like state. Notwithstanding their autologous origin and their potential …

Antioxidant strategy to prevent simulated microgravity-induced effects on bone osteoblasts

C Morabito, S Guarnieri, A Cucina, M Bizzarri… - International Journal of …, 2020 - mdpi.com
The effects induced by microgravity on human body functions have been widely described,
in particular those on skeletal muscle and bone tissues. This study aims to implement …

Shaping the cell and the future: recent advancements in biophysical aspects relevant to regenerative medicine

ML Hart, JC Lauer, M Selig, M Hanak… - Journal of Functional …, 2017 - mdpi.com
In a worldwide effort to generate clinically useful therapeutic or preventive interventions,
harnessing biophysical stimuli for directing cell fate is a powerful strategy. With the vision to …

Label-free morphology-based prediction of multiple differentiation potentials of human mesenchymal stem cells for early evaluation of intact cells

H Sasaki, I Takeuchi, M Okada, R Sawada, K Kanie… - PloS one, 2014 - journals.plos.org
Precise quantification of cellular potential of stem cells, such as human bone marrow–
derived mesenchymal stem cells (hBMSCs), is important for achieving stable and effective …