Sex differences in type 2 diabetes

A Kautzky-Willer, M Leutner, J Harreiter - Diabetologia, 2023 - Springer
The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually
diagnosed at a younger age and lower body fat mass than women. Worldwide, an estimated …

Influence of gender in diabetes mellitus and its complication

T Ciarambino, P Crispino, G Leto… - International journal of …, 2022 - mdpi.com
In medicine, there is growing evidence that gender differences are important and lead to
variations in the pathophysiology and treatment of many diseases with traits that appear to …

[HTML][HTML] Editor's choice--European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of asymptomatic lower limb peripheral …

J Nordanstig, CA Behrendt, I Baumgartner… - European Journal of …, 2024 - Elsevier
BIOTRONIK's First in Man study of the Passeo-18 LUX drug releasing PTA Balloon Catheter
vs. the uncoated Passeo-18 PTA balloon catheter in subjects requiring revascularisation of …

Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms

L Xu, Y Li, Y Dai, J Peng - Pharmacological research, 2018 - Elsevier
Epidemiological studies have implied that diabetes mellitus (DM) will become an epidemic
accompany with metabolic and endocrine disorders worldwide. Most of DM patients are …

Bridging the Gap” Everything that Could Have Been Avoided If We Had Applied Gender Medicine, Pharmacogenetics and Personalized Medicine in the Gender …

D Gemmati, K Varani, B Bramanti, R Piva… - International journal of …, 2019 - mdpi.com
Gender medicine is the first step of personalized medicine and patient-centred care, an
essential development to achieve the standard goal of a holistic approach to patients and …

Sex difference in human diseases: mechanistic insights and clinical implications

Y Shi, J Ma, S Li, C Liu, Y Liu, J Chen, N Liu… - … and Targeted Therapy, 2024 - nature.com
Sex characteristics exhibit significant disparities in various human diseases, including
prevalent cardiovascular diseases, cancers, metabolic disorders, autoimmune diseases …

Activated AMPK mitigates diabetes-related cognitive dysfunction by inhibiting hippocampal ferroptosis

Z Xie, X Wang, X Luo, J Yan, J Zhang, R Sun… - Biochemical …, 2023 - Elsevier
Clinical and preclinical interest in Type 2 diabetes (T2D)-associated cognitive dysfunction
(TDACD) has grown in recent years. However, the precise mechanisms underlying TDACD …

Sex differences in cardiovascular effectiveness of newer glucose‐lowering drugs added to metformin in type 2 diabetes mellitus

V Raparelli, M Elharram, CS Moura… - Journal of the …, 2020 - Am Heart Assoc
Background Randomized controlled trials showed that newer glucose‐lowering agents are
cardioprotective, but most participants were men. It is unknown whether benefits are similar …

Sex differences in autophagy-mediated diseases: toward precision medicine

D Shang, L Wang, DJ Klionsky, H Cheng, R Zhou - Autophagy, 2021 - Taylor & Francis
Nearly all diseases in humans, to a certain extent, exhibit sex differences, including
differences in the onset, progression, prevention, therapy, and prognosis of diseases …

Cellular interplay between cardiomyocytes and non-myocytes in diabetic cardiomyopathy

RJ Phang, RH Ritchie, DJ Hausenloy… - Cardiovascular …, 2023 - academic.oup.com
Patients with Type 2 diabetes mellitus (T2DM) frequently exhibit a distinctive cardiac
phenotype known as diabetic cardiomyopathy. Cardiac complications associated with T2DM …